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Tag: malaria

  • Episodes

TWiP 103: Scroll down, please

  • February 13, 2016
  • Tagged as: Africa, cerebral malaria, Echinococcus, eukaryote, hydatid disease, malaria, parasite, parasitism, Plasmodium falciparum, single nucleotide polymorphism
TWiP

The TWiP-scholars solve the case of the Housewife from Kolkata, discuss mutations in the IL17 gene associated with cerebral malaria, and hear a case presentation from guest Michael Libman.

2 Replies
  • Episodes

TWiP 100: Driving past a milestone

  • January 9, 2016
  • Tagged as: Anopheles stephensi, Cas9, case study, CRISPR, gene conversion, gene drive, malaria, mosquito, parasite, parasitism, parasitology, population modification
TWiP

The TWiP trifecta solves the case of the Woman from Bolivia with Belly Pain, and discuss a method for population modification of malaria mosquitoes using a Cas9-mediated driver gene.

2 Replies
  • Episodes

TWiP 97: The seven year itch

  • October 17, 2015
  • Tagged as: alpha-gal, artemisinin, complement, gut microbiota, ivermectin, malaria, natural antibody, Nobel Prize, parasite, parasitism, Plasmodium, scabies, William Campbell
TWiP

The paratenic hosts reveal a case of scabies in the Traveling Salesman, and discuss a role for natural antibody in protection from infection with Plasmodium.

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  • Episodes

TWiP 91: Born to deform

  • June 20, 2015
  • Tagged as: cAMP, Cialis, deformability, erythrocyte, gametocyte, malaria, parasite, parasitism, phosphodiesterase, Plasmodium falciparum, protein kinase A, sildenafil, transmission, Viagra

Vincent, Dickson, and Daniel review how Viagra might be used to block transmission of Plasmodium falciparum, and introduce a new case study.

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  • Episodes

TWiP 90: A carbuncle is a large furuncle

  • May 30, 2015
  • Tagged as: CD44, CD55, erythrocyte, forward genetic screen, invasion, malaria, parasite, parasitism, Plasmodium falciparum, siRNA

Vincent, Dickson, and Daniel discuss identification of an erythrocyte protein essential for invasion of Plasmodium falciparum, and introduce a new case study.

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  • Episodes

TWiP 84: Bigfoot

  • February 28, 2015
  • Tagged as: lymphatic filariasis, malaria, nanobody, P. vivax, parasite, parasitism, single domain antibody, symbiont, trypanolytic, trypanosome, Wuchereria bancroftii

Vincent, Dickson, and Daniel consider the delivery of anti-trypanosome nanobodies to the tsetse fly via a bacterial symbiont, and present a new case study.

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  • Episodes

TWiP 83: Hidden costs of infection

  • February 23, 2015
  • Tagged as: fitness cost, life span, longevity, malaria, parasite, parasitism, senescence, telomere

Vincent, Dickson, and Daniel present a new case study, and discuss the effect of chronic malaria infection on wild warbler life span and telomere degradation.

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  • Episodes

TWiP 78: Eau de rodent

  • October 29, 2014
  • Tagged as: attraction, host, malaria, odors, parasite, parasitism, Plasmodium, rodent, scents

Vincent and Dickson discuss how malaria parasites induce odors in their rodent hosts that attract mosquitoes.

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  • Episodes

TWiP 74: Nature has all the answers, what is your question?

  • July 4, 2014
  • Tagged as: antigen, egress, malaria, parasite, parasitism, Plasmodium falciparum, red blood cell, schizont, vaccine

Vincent and Dickson review a novel malaria vaccine candidate comprising a parasite protein involved in egress from red blood cells.

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  • Episodes

TWiP 69: Malaria rising

  • March 29, 2014
  • Tagged as: climate change, global warming, malaria, parasite, parasitism, Plasmodium falciparum, spatiotemporal

Vincent and Dickson discuss an increase in the altitude of malaria distribution in warmer years in the highlands of Colombia and Ethiopia.

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Christina Naula, Ph.D.


Daniel Griffin, M.D.,

Vincent Racaniello, Ph.D.


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