Oxamniquine structure

Hosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson explain the genetic and molecular basis of drug resistance in Schistosoma mansonii.

Download TWiP #67 (55 MB .mp3, 76 minutes).

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Nitrile-group-2D

Hosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson discuss reversible inhibitors of cruzipain as new drugs for treating Chagas disease.

Download TWiP #66 (74 MB .mp3, 103 minutes).

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journal.pone.0020193.g001Hosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson consider the effects of climate change on parasitic diseases.

Download TWiP #65 (60 MB .mp3, 83 minutes).

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Dickson’s Pick

Neglected by Shelly Xie (YouTube)

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journal.ppat.1003757.s003Hosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson review three novel approaches to antimalarial chemotherapy.

Download TWiP #64 (70 MB .mp3, 97 minutes).

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 Cornelius Dr. ZaiusHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson discuss evidence that the malaria parasite originated in gorillas.

Download TWiP #63 (70 MB .mp3, 97 minutes).

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Screenshot 2013-10-30 22.06.22Hosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson discuss the high diversity of malaria parasites in West African bats, and a vaccine against hookworm.

Download TWiP #62 (70 MB .mp3, 96 minutes).

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journal.pone.0007288.g004Hosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson review examples of paleoparasitology, the detection of parasites in archaeological material.

Download TWiP #61 (54 MB .mp3, 75 minutes).

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cat-and-mouseHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson discuss how infection with Toxoplasma gondii causes mice to lose their aversion to cat urine, even after the parasites have been cleared.

Download TWiP #60 (51 MB .mp3, 70 minutes).

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Listener Pick

BlaineThe Worm Within

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Apicomplexa structureHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson update the multistate outbreak of cyclosporiasis, discuss the avian malaria parasite P. lophurae, and review protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine.

Download TWiP #59 (60 MB .mp3, 84 minutes).

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IMG 4428Hosts: Vincent Racaniello and Dickson Despommier

Guest: Cali Despommier

Vincent and Dickson update the multistate outbreak of cyclosporiasis, and Dickson reads a chapter from his new book.

Download TWiP #58 (68 MB .mp3, 94 minutes).

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