plasmodium bloodHosts: Vincent RacanielloDickson Despommier, and Daniel Griffin

Vincent, Dickson, and Daniel discuss identification of an erythrocyte protein essential for invasion of Plasmodium falciparum, and introduce a new case study.

Download TWiP #90 (88 MB .mp3, 121 minutes).

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differential_counterHosts: Vincent RacanielloDickson Despommier, and Daniel Griffin

Vincent, Dickson, and Daniel reveal last week’s case study and introduce a new one concerning a patient who traveled to Belize.

Download TWiP #89 (68 MB .mp3, 94 minutes).

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mitogenic pathwayHosts: Vincent RacanielloDickson Despommier, and Daniel Griffin

Vincent, Dickson, and Daniel discuss how a secreted protein from the protozoan parasite Theileria transforms its host cells via a cellular proto-oncogene.

Download TWiP #88 (82 MB .mp3, 114 minutes).

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TrypanosomaBrucei ProcyclicTrypomastigote SEMHosts: Vincent RacanielloDickson Despommier, and Daniel Griffin

Vincent, Dickson, and Daniel review new insight into antigenic variation in trypanosomes, reveal the difficult solution to the last case study, and  present another mystery for your solving.

Download TWiP #87 (55 MB .mp3, 77 minutes).

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loa microfilariaeHosts: Vincent RacanielloDickson Despommier, and Daniel Griffin

Vincent, Dickson, and Daniel discuss how filarial infection modulates the immune response to mycobacterial infection, and reveal a new case study.

Download TWiP #86 (90 MB .mp3, 125 minutes).

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crawfishHosts: Vincent RacanielloDickson Despommier, and Daniel Griffin

Vincent, Dickson, and Daniel explain how trypanolytic factor forms membrane channels to lyse trypanosomes, and present a new case study.

Download TWiP #85 (79 MB .mp3, 110 minutes).

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500px-Heavy_chain_and_common_antibody.svgHosts: Vincent RacanielloDickson Despommier, and Daniel Griffin

Vincent, Dickson, and Daniel consider the delivery of anti-trypanosome nanobodies to the tsetse fly via a bacterial symbiont, and present a new case study.

Download TWiP #84 (78 MB .mp3, 106 minutes).

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Drosselrohrsanger Great reed warblerHosts: Vincent RacanielloDickson Despommier, and Daniel Griffin

Vincent, Dickson, and Daniel present a new case study, and discuss the effect of chronic malaria infection on wild warbler life span and telomere degradation.

Download TWiP #83 (69 MB .mp3, 96 minutes).

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fasciola adultHosts: Vincent RacanielloDickson Despommier, and Daniel Griffin

Vincent, Dickson, and Daniel solve last week’s case study, present a new one, and reveal how secreted proteins from a helminth prevent diabetes in mice.

 Download TWiP #82 (72 MB .mp3, 100 minutes).

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640px-Serengeti Bueffel1Hosts: Vincent RacanielloDickson Despommier, and Daniel Griffin

Vincent, Dickson, and Daniel provide the solution to last week’s case study, present a new one, and discuss how immune suppression by nematodes increases tuberculosis fatality in African buffalo.

Download TWiP #81 (72 MB .mp3, 100 minutes).

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