The TWiP professors solve the case of the Ugandan Child with Splenomegaly, and reveal that mutations in the P. falciparum genome that confer artemisinin resistance interfere with endocytic uptake of hemoglobin.
TWiP 85: Channeling tryps
- March 14, 2015
- Tagged as: ApoL1, channel, crawfish, endocytosis, paragonimiasis, parasite, parasitism, pH, trypanolytic factor, trypanosome
Vincent, Dickson, and Daniel explain how trypanolytic factor forms membrane channels to lyse trypanosomes, and present a new case study.