Dickson, Daniel and Vincent solve the case of the Baby with Hydrocephalus, and present a new clinical case for listeners to solve.
TWiP 187: Granny’s granuloma
- August 29, 2020
- Tagged as: Chagas disease, granuloma, heme oxygenase, leishmaniasis, malaria, parasite, parasitism, parasitology, Toxocara
Dickson, Daniel and Vincent solve the case of the Middle Aged Woman with Loss of Vision in One Eye, and discuss the role of heme oxygenase in the various protozoan infections.
Dickson, Daniel and Vincent solve the case of the Elder Gardener Feeling Poorly, and discuss the three-dimensional ultrastructure of Plasmodium falciparum during cytokinesis.
Dickson, Daniel and Vincent solve the case of the Wife of a Guy with Cyclospora Diarrhea, and discuss the discovery of an intrinsic oscillator that drives the bloodstream stage cycle of the malaria parasite.
TWiP 184: The hunter gets captured by the game
- June 6, 2020
- Tagged as: Anopheles, COVID-19, cyclospora, endosymbiont, malaria, microsporidian, mosquito, parasite, parasitism, parasitology, Plasmodium, watery diarrhea, wolbachia
Dickson, Daniel and Vincent solve the case of the Safari Goer With Watery Diarrhea, and explain how a microsporidian endosymbiont of Anopheles mosquitoes might impair the transmission of malaria.
TWiP 183: When they dry they die
- May 8, 2020
- Tagged as: Enterobius vermicularis, nematode, ONP, parasite, parasitism, protease, roundworm, whipworm
Dickson, Daniel and Vincent solve the case of the Female with Itchy Anus, and reveal the structure of a roundworm membrane protein involved in digestion of nutrients.
Dickson, Daniel and Vincent solve the case of the Ugandan Volunteer With Morning Bites and discuss integration of HIV-1 into the Schistosome genome, with a sprinkling of COVID-19 throughout.
TWiP 181: Daniel’s drive-through
- March 14, 2020
- Tagged as: colony collapse, COVID-19, dsRNA, honeybee, parasite, parasitism, parasitology, SARS-CoV-2
Dickson, Daniel and Vincent solve the case of the Two Volunteers With Watery Diarrhea, discuss diagnosis of SARS-CoV-2 in the New York area, and reveal an approach to preventing honeybee colony collapse by imbuing their gut bacteria with the ability to produce antiviral and antiparasite double-stranded RNAs.
The TWiP professors solve the case of the Ugandan Child with Splenomegaly, and reveal that mutations in the P. falciparum genome that confer artemisinin resistance interfere with endocytic uptake of hemoglobin.
The TWiP DVD solve the case of the Child Who Passed Worms, and discuss a non-human primate model for severe malarial anemia.
