The TWiP quadfecta solves the case of the Traveler With Watery Diarrhea, and reveals that a heat-shock response regulated by a transcription factor protects human malaria parasites from the high temperatures of fever.
TWiP solves the case of the Adventurous Eater with Areas of Swelling, and discusses an experimental Trypanosoma vivax vaccine comprising an invariant flagellum antigen.
TWiP solves the case of the Homeless Man With Skin Issues, and discusses an experimental mRNA based malaria vaccine.
Christina returns to the TWiP trifecta to solve the case of the Beachgoer with Red Lines on Her foot, and an experimental malaria vaccine based on the junctional region of the circumsporozoite protein displayed on a virus-like particle.
TWiP 194: Eye had a corneal scraping
- April 24, 2021
- Tagged as: Acanthamoeba, flavivirus, helminth, IL-4, parasite, parasitism, parasitology, tuft cell, West Nile Virus
TWiP solves the case of the Long Island Man with Unilateral Eye Pain, followed by a discussion of how enteric helminth coinfection enhances host susceptibility to West Nile virus by a tuft cell-IL-4 receptor signaling axis.
TWiP 193: A serpiginous trail
- March 29, 2021
- Tagged as: Blastocystys, COVID-19, parasite, parasitism, parasitology, steroid, Strongyloides
Audun returns to help solve the case of the Ecuadorean Gentleman Treated for COVID-19, followed by a discussion of the interaction of Blastocystis with the intestinal microbiota and the immune system, and of course a new clinical case from Daniel.
TWiP 192: Towel off vigorously
- February 15, 2021
- Tagged as: parasite, parasitism, parasitology, schistosomiasis
The TWiPers solve the case of the Teenager in Malawi with Red Urine, then Audun joins to present our clinical case for this episode.
TWiP 191: Dickson’s ocular anomaly
- January 11, 2021
- Tagged as: ocular larva migrans, parasite, parasitism, parasitology, RNAseq, S. mansoni
The TWiPers solve the case of the Rural Man from North Carolina with Blurred Vision, and discuss the results of single-cell RNA sequencing of Schistosoma mansoni.
TWiP 190: But Doc, what could it be?
- December 8, 2020
- Tagged as: abdominal mass, COVID-19, Echinococcus, hydatid cyst, malaria, NGO, pandemic, parasite, parasitism, parasitology
Christina from Glasgow returns to help the TWiPlets solve the case of the Ghanian Woman with Abdominal Mass, followed by discussion of the impact of COVID-19 on malaria morbidity and mortality in Africa.
TWiP 189: Toe jammin’
- November 7, 2020
- Tagged as: body rash, ivermectin, parasite, parasitism, parasitology, Sarcoptes scabei, scabies
Christina from Glasgow joins the TWiPlets to solve the case of the Elderly Gentlemen with Full Body Rash, and to present a new clinical case for listeners to solve.
