TWiP solves the case of the Long Island Man with Unilateral Eye Pain, followed by a discussion of how enteric helminth coinfection enhances host susceptibility to West Nile virus by a tuft cell-IL-4 receptor signaling axis.
Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin
Guest: Christina Naula
Click arrow to play
Download TWiP #194 (46 MB .mp3, 76 minutes)
Subscribe (free): iTunes, Google Podcasts, RSS, email
Links for this episode
- PWB on Facebook, Instagram, Twitter
- Helminth infection enhances West Nile viruses pathogenesis (Cell)
- Hero: Franz Von Lichtenberg
- Letters read on TWiP 194
Become a patron of TWiP
Case Study for TWiP 194
Woman in 40s, on return from Puerto Rico where she often went. Went to local beaches, brought their dogs. Noticed problem on foot, raised red serpiginous lines, slowly moving all over the foot. Bloodwork showed elevated eosinophils.
Send your case diagnosis, questions and comments to firstname.lastname@example.org
Music by Ronald Jenkees
Most probably the nematode Ancylostoma braziliense in its third larval stage. It is the most common hook worm in the area. Checks out with dogs, moist sand in warm weather as in Puerto Rico, possible bare feet in a recreation area, and serpiginous lines or “creeping eruptions” wich are simptoms in human skin. Eosinophilia is seen in parasitic infections. It seems A.caninum is less frequent, as is Uncinaria stenocephala.