TWiP 194: Eye had a corneal scraping

April 24, 2021

TWiP solves the case of the Long Island Man with Unilateral Eye Pain, followed by a discussion of how enteric helminth coinfection enhances host susceptibility to West Nile virus by a tuft cell-IL-4 receptor signaling axis.

Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin

Guest: Christina Naula

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Download TWiP #194 (46 MB .mp3, 76 minutes)

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Case Study for TWiP 194

Woman in 40s, on return from Puerto Rico where she often went. Went to local beaches, brought their dogs. Noticed problem on foot, raised red serpiginous lines, slowly moving all over the foot. Bloodwork showed elevated eosinophils. 

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Music by Ronald Jenkees

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2 comments on “TWiP 194: Eye had a corneal scraping

  1. Gabriel Jimenez Apr 27, 2021

    Most probably the nematode Ancylostoma braziliense in its third larval stage. It is the most common hook worm in the area. Checks out with dogs, moist sand in warm weather as in Puerto Rico, possible bare feet in a recreation area, and serpiginous lines or “creeping eruptions” wich are simptoms in human skin. Eosinophilia is seen in parasitic infections. It seems A.caninum is less frequent, as is Uncinaria stenocephala.