TWiM 280: They forgot to divide

TWiM explains how magnesium modulates cell division frequency of a soil bacillus, and killing of fungi by Acinetobacter baumannii via a Type VI DNase effector.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

Right click to download TWiM #280 (36 MB .mp3, 59 minutes)

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•Magnesium modulates cell division frequency (J Bacteriol)
•A. baumannii kills fungi (mBio)

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 279: A road map for successful phage therapy

TWiM describes successful phage therapy against a mycobacterial lung infection, and how encapsulation of the cell wall protects S. pneumoniae from its major peptidoglycan hydrolase and host defenses.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

Right click to download TWiM #279 (36 MB .mp3, 59 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 278: Bacteria sing the blues

TWiM explores the relationship between the gut microbiome and depressive symptoms, and how purine nucleotides act as adjuvants to antibiotics.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM #278 (36 MB .mp3, 59 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 277: To stop or not to stop

On this episode of TWiM, we reveal widespread stop-codon recoding in bacteriophages that may regulate translation of lytic genes, and how Staphylococcus aureus inhibits Pseudomonas aeruginosa growth.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM #277 (48 MB .mp3, 67 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 276: Bacterial multicellularity near an underground stream

TWiM presents evidence that over half of human pathogenic diseases are impacted by climate change, and considers how a novel prokaryote discovered next to an underground stream illuminates the pathway to multicellularity.

Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin

Right click to download TWiM #276 (48 MB .mp3, 67 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 275: The myth of clonality

TWiM reveals high rates of co-transformation of plasmids in E. coli overturns the clonality myth, and bacterial membrane vesicles as a novel strategy for extrusion of the antimicrobial bismuth in H. pylori.

Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin

Right click to download TWiM #274 (48 MB .mp3, 66 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 274: Bacterial endosymbionts block giant viruses

Mark Martin returns to TWiM to join the discussion of how to design a complex gut microbiome, and protection of protists from virus infection by intracellular bacterial symbionts.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

Guest: Mark O. Martin

Right click to download TWiM #274 (42 MB .mp3, 58 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 273: The value of wiping

TWiM reveals how to inactivate norovirus on formica surfaces, and how to achieve antibiotic resistance by suppression of a frameshift mutation in an essential gene.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson, and Petra Levin

Right click to download TWiM #273 (38 MB .mp3, 52 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 272: Metabolism’s got rhythm

TWiM explores the activation of  natural product synthesis using CRISPR interference in Streptomyces, and how light/dark and temperature cycling modulate electron flow in Pseudomonas aeruginosa biofilms.

Hosts: Vincent Racaniello, Michele Swanson, and Petra Levin

Right click to download TWiM #272 (38 MB .mp3, 52 minutes)

Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email.

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 271: Microbe vs microbe

TWiM presents a novel mucosal COVID-19 vaccine based on a bacteriophage capsid, and potentiation of C. difficile infection severity by the gut bacterial community.

Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Right click to download TWiM #271 (38 MB .mp3, 52 minutes)

Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email.

Become a Patron of TWiM!

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

The Hosts of TWiM

Petra Levin, Ph.D.


Michele Swanson, Ph.D.


Michael G. Schmidt, Ph.D.


Vincent Racaniello, Ph.D.


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Please note that content in MicrobeTV podcasts should not be construed as medical advice.