TWiM 211: Bacteria, colon cancer, and fire blight

The Fellowship of the TWiM reveal that colorectal cancer-associated microbiota are associated with higher numbers of methylated genes in colonic mucosa, and identification of metabolites needed by the fire blight disease bacterium for virulence in apples.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt

Right click to download TWiM#211 (57 MB .mp3, 78 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 210: The Waze of microbes

The Microbial Comrades present the oldest osteosynthesis in history, and how a small molecule produced by stressed bacteria is a warning signal that repels healthy populations to promote their survival.

Bone with copper plate from Varnhem Monastery, 1260-1527
Bone with copper plate from Varnhem Monastery, 1260-1527

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt

Right click to download TWiM#210 (37 MB .mp3, 76 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 209: Resuscitating persisters and flagellotrophic phage

The TWiM team reveals how ribosome modification resuscitates bacterial persister cells, and explain how a phage tail fiber protein exploits rotation of flagella to move towards the cell membrane.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt

Right click to download TWiM#209 (47 MB .mp3, 65 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 208: Georgia Tech microbial

At Georgia Tech, members and trainees of the Center for Microbial Dynamics and Infection discuss the identification of pathogen essential genes during coinfections, and how coral management can improve coral defenses against pathogens.

Hosts: Vincent Racaniello, Michele Swanson and Michael Schmidt

Guests: Deanna Beatty, Mark Hay, Gina Lewin, Frank Stewart, and Marvin Whiteley

Right click to download TWiM#208 (33 MB .mp3, 67 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 207: Partnerships to advance public health

From ASM Microbe 2019 in San Francisco, Vincent speaks with Victoria McGovern, Carl Nathan, and Dan Portnoy about advancing human health through innovative collaborations.

Host: Vincent Racaniello

Guests: Victoria McGovern, Carl Nathan, and Dan Portnoy

Right click to download TWiM#207 (33 MB .mp3, 67 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 206: Bacteria send nucleotide signals


The TWiM holobionts pay tribute to Stuart Levy, and reveal the remarkably diverse array of cyclic nucleotides synthesized by bacteria that likely mediate interactions with animal and plant hosts.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt

Right click to download TWiM#206 (47 MB .mp3, 65 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 205: Asgards meet the Tardigrades

The tetracoccal TWiM team visits Tardigrades on the Moon, and the twelve year quest to isolate an archaeon that provides insights into the emergence of the first eukaryotic cell.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt

Right click to download TWiM#205 (49 MB .mp3, 67 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 204: Programmable bacteria for antitumor immunity

Vincent meets up with Nick and Tal to explain how they engineered E. coli to lyse within tumors and deliver an antibody that causes tumor regression in mice.

Host: Vincent Racaniello

Guests: Nicholas Arpaia and Tal Danino

Right click to download TWiM#204 (49 MB .mp3, 68 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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TWiM 203: A magnetotacic consortium under the sea

The TWiM team reveals thousands of small novel genes in the human microbiome, and a mutualistic symbiosis between marine protists covered with magnetosome-containing bacteria.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt

Right click to download TWiM#203 (29 MB .mp3, 58 minutes)

Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

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Links for this episode

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM 202: This frass doesn’t stink


Julie joins the TWiM team to reveal how microbiome and gut anatomy of a wood-feeding beetle promotes lignocellulose deconstruction, and bacteria that degrade PET plastic.

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson and Michael Schmidt

Guest: Julie Wolf

Right click to download TWiM#202 (30 MB .mp3, 60 minutes)

Subscribe to TWiM (free) on iTunes, Google Podcasts, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

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Links for this episode

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

The Hosts of TWiM

Petra Levin, Ph.D.


Michele Swanson, Ph.D.


Michael G. Schmidt, Ph.D.


Vincent Racaniello, Ph.D.


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