TWiM describes a potential connection between a bacterial protein that damages DNA and human cancers, and how to synthesize antimiicrobial natural products from reconstructed bacterial genomes of the Middle and Upper Paleolithic.
TWiM reveals a study showing that positive interactions among bacteria are far more common than previously thought, and how acquisition of a single gene enabled Yersinia pestis to expand the range of mammalian hosts that sustain flea-borne plague.
The TWiM team reviews the coronavirus outbreak that began in Wuhan, China, and the finding that an IRF deficiency underlies Whipple’s disease.
The TWiM holobionts pay tribute to Stuart Levy, and reveal the remarkably diverse array of cyclic nucleotides synthesized by bacteria that likely mediate interactions with animal and plant hosts.
The Hosts of TWiM
Petra Levin, Ph.D.
Michele Swanson, Ph.D.
Michael G. Schmidt, Ph.D.
Vincent Racaniello, Ph.D.