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Category: Episode

  • Episode

TWiEVO 38: Evolving to evolve

  • December 24, 2018
  • Tagged as: anti-evolution drug, antibiotic resistance, bacteria, evolution, evolvability, Mfd protein, mutagenesis, mutation rate, RpoB, transcription-coupled repair, UvrA

Nels and Vincent reveal a highly conserved protein that acts as an evolvability factor, increasing mutation and the ability of bacteria to become resistant to antibiotics.

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  • Episode

TWiEVO 37: A tangled tree on the Quammens

  • November 17, 2018
  • Tagged as: Carl Woese, Charles Darwin, David Quammen, evolution, evolutionary tree, horizontal gene transfer, Lynn Margulis, phylogenomics, The Tangled Tree

David Quammen joins Nels and Vincent to talk about his new book, A Tangled Tree, including evolutionary trees, Carl Woese, Lynn Margulis, horizontal gene transfer, and much more.

2 Replies
  • Episode

TWiEVO 35: Strawberry sex chromosomes forever

  • September 21, 2018
  • Tagged as: Dioecy, diversity, evolution, fertilization, genome, Homoeologs, Homomorphic, jumping sex genes, octoploid, parasites, reproduction, sex, sex chromosome, strawberry

Nels and Vincent reveal that female-specific DNA associated with sex in strawberries has repeatedly changed its genomic location, possibly linking new genes with sex.

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  • Episode

TWiEVO 34: You don’t know what you’ve got ‘til it’s PON

  • August 16, 2018
  • Tagged as: agricultural runoff, cetacean, evolution, gene loss, marine mammal, natural selection, organophosphorus, paraoxonase, pesticide, pinniped, sirenian

Nels and Vincent discuss how the loss of an enzyme in marine mammals millions of years ago now makes them at risk for neurotoxicity caused by human-made organophosphorous pesticides.

2 Replies
  • Episode

TWiEVO 33: Fly by virus

  • July 24, 2018
  • Tagged as: behavior modification, Coccinellidae, Cordyceps, diptera, Entomophthora muscae, evolution, fungus, iflavirus, microbial control of hosts, viral, virology, virus, viruses

Nels and Vincent are astounded by the finding of an insect-derived virus in a fungus that manipulates the behavior of flies.

1 Reply
  • Episode

TWiEVO 32: Never not neutral

  • June 19, 2018
  • Tagged as: adaptation, evolution, mutation, natural selection, neutral theory of evolution, population genetics, spandrel, TWiEVO

Matt joins Nels and Vincent to discuss the neutral theory of evolution and its rejection in light of genome-scale data.

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  • Episode

TWiEVO 30: Driving Miss Maize-y

  • April 21, 2018
  • Tagged as: chromosome segregation, corn, evolution, Kindr, kinesin, maize, natural selection, neocentromere, non-Mendelian inheritance

Nels and Vincent reveal how a motor protein in corn causes preferential transmission of chromosomes to egg cells, leading to non-Mendelian inheritance

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  • Episode

TWiEVO 29: Evolution on the wing

  • March 21, 2018
  • Tagged as: blood feeding, blood meal, evolution, evolution of virulence, house finch, incomplete immunity, mosquito, mycoplasma, natural selection, nonbiting mosquito, transcriptome

Nels and Vincent discuss the evolution of blood feeding to nonbiting in a mosquito, and evolution of bacterial virulence in the house finch caused by incomplete host immunity.

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  • Episode

TWiEVO 28: Genetics of skin pigmentation in Africa

  • February 27, 2018
  • Tagged as: Africa, epidermal pigmentation, gene, genome, genotype, melanin, melanocyte, skin pigmentation, ultraviolet response

Sarah Tishkoff joins Nels and Vincent to explain work from her laboratory on the genetic basis of skin pigmentation in Africans.

2 Replies
  • Episode

TWiEVO 27: Coldevo

  • January 13, 2018
  • Tagged as: cold sensitivity, evolution, hibernation, ion channel, somatosensory neuron, Syrian hamster, thirteen-lined ground squirrel, TRPM8

Taking a cue from the recent frigid weather, Nels and Vincent explore how modifications of a neuronal cold-sensing channel regulate diminished cold sensitivity in hibernating mammals.

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The Hosts of TWiEVO

Nels Elde, Ph.D.


Vincent Racaniello, Ph.D.


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