TWiV 488: Who nose if it will work in humans

April 8, 2018

Olfactory virus spreadThe TWiV team reveals that recent mumps virus outbreaks in the US are due to waning vaccine efficacy, and an intranasally delivered small interfering RNA that controls West Nile infection in the brain.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, and Kathy Spindler

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Download TWiV 488 (62 MB .mp3, 102 min)
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Intro music is by Ronald Jenkees.

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2 comments on “TWiV 488: Who nose if it will work in humans

  1. Chad Yanyatan Apr 13, 2018

    This was one of the best episodes I’ve listened to in a while. It was very easy to understand and it will be very interesting to see if it will actually work in humans. There’s a famous joke in biology that goes: “We have cured every disease out there, but in mice”. Also, I would like to recommend an article my professor has sent me. It mentions how a virus hijacks the host in order to increase actin polymerization in the “nucleus”. Fascinating stuff. Thanks a lot for all of your efforts. Greetings from Kean University.
    https://www.ncbi.nlm.nih.gov/pubmed/17053146

    • profvrr Apr 14, 2018

      Thanks Chad! You are not too far from me. We’ve been making a conscious effort lately explain things more clearly, avoiding the ‘weeds’. Vincent.