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Tag: siRNA

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TWiV 488: Who nose if it will work in humans

  • April 8, 2018
  • Tagged as: encephalitis, epidemiology, immunity, mumps, mumps outbreaks, nasal spray, olfactory mucosa, rabies virus, siRNA, vaccine efficacy, vaccine waning, viral, virology, virus, viruses, west nile virus

The TWiV team reveals that recent mumps virus outbreaks in the US are due to waning vaccine efficacy, and an intranasally delivered small interfering RNA that controls West Nile infection in the brain.

2 Replies
  • Episodes
  • Netcast

TWiV 482: Don’t EVEome without antibody expressed

  • February 25, 2018
  • Tagged as: asymptomatic, ebolavirus, EBOV, ELISA, endogenous viral element, EVEome, immunity, mosquito, piRNA, piwi, piwi-interacting RNA, serology, siRNA, transmission, viral, virology, virus, viruses

The TWiV Masters discuss serologic evidence of Ebolavirus infection in a population with no outbreaks, and the set of endogenous viral elements in the mosquito genome.

1 Reply
  • Episodes
  • Netcast

TWiV 449: The sound of non-silencing

  • July 9, 2017
  • Tagged as: argonaute, dicer, enterovirus 71, facial appearance, impression formation, innate immunity, RNA interference, RNAi, science communication, siRNA, social cognition, viral, viral suppressor of silencing, virology, virus
TWiV

The TWiV Council explores the finding that facial appearance affects science communication, and evidence that RNA interference confers antiviral immunity in mammalian cells.

2 Replies
  • Netcast

TWiV 140: An aptitude for microbicides

  • July 3, 2011
  • Tagged as: AIDS, aptamer, hiv, judy lieberman, microbicide, RNA interference, siRNA, vaginal gel, viral, virology, virus

Vincent, Alan, Rich, and Judy Lieberman review the use of CD4 aptamer-siRNA chimeras to inhibit HIV transmission.

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  • Netcast

TWiV 138: RISCy business with Raul Andino

  • June 19, 2011
  • Tagged as: argonaute, dicer, drosophila, fly, immunity, innate immunity, raul andino, risc, RNA interference, siRNA, viral, virology, virus

Vincent meets up with Raul Andino in San Francisco to discuss the RNAi-based antiviral defense system of Drosophila, the fruit fly, and how it is antagonized by viruses.

2 Replies
  • Netcast

TWiV 114: Ten out of ’10

  • January 2, 2011
  • Tagged as: CFS, circovirus, david baltimore, dengue, endogenous virus, influenza, miRNA, plaque, Polio, prostate cancer, retrovirus, siRNA, Vaccine, viral, virology, virus, XMRV

Vincent, Alan, and Rich revisit ten compelling virology stories of 2010.

4 Replies
  • Netcast

TWiV 89: Where do viruses vacation?

  • July 4, 2010
  • Tagged as: CFS, Chronic Fatigue Syndrome, Ebola, ebolavirus, entry, H1N1, influenza, mecfs, pandemic, reassortment, reovirus, retrovirus, seasonal influenza, siRNA, Swine, swine flu, viral, virology, virus, XMRV

Vincent and Alan review recent findings on the association of the retrovirus XMRV with ME/CFS, reassortment of 2009 pandemic H1N1 influenza virus in swine, and where influenza viruses travel in the off-season.

18 Replies

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