TWiV 418: Of mice and MERS

December 4, 2016

Wall of Semliki and ChikungunyaHosts: Vincent RacanielloDickson DespommierAlan DoveRich Condit, and Kathy Spindler

The TWiVsters describe a new animal model for MERS coronavirus-induced acute respiratory distress syndrome, produced by CRISPR/Cas9 editing of the mouse gene encoding an ortholog of the virus receptor.

Click arrow to play
Download TWiV 418 (63 MB .mp3, 104 min)
Subscribe (free): iTunesRSSemail

Become a patron of TWiV!

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world’s best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at and use the promo code MICROBE. 0:25, 44:10

This show is sponsored by Drobo, a family of safe, expandable , yet simple to use storage arrays. Drobos are designed to protect your important data forever. This Holiday season give someone a Drobo to keep all their files and memories safe forever. TWiV listeners can save 20% or more off of their purchase of a Drobo 5D, Drobo 5Dt, Drobo 5N, or any 8-drive or 12-drive system at by December 31, 2016 using discount code MICROBE20. 0:50, 1:06:20

Register for ASV 2017 at Madison, Wisconsin

Weekly Science Picks 42:25, 1:29:20

Alan – Human population through time
Dickson – Every Orbit Cassini Has Taken
Rich – OK GO: Walk Her Walk
Kathy – Medieval Bestiary Online
Vincent – Can You Out-Science an Eighth Grader? and Stitchen Pox (jpg)

Listener Pick

HannahBioart and Bacteria

Send your virology questions and comments to

Leave a Reply

Your email address will not be published. Required fields are marked *

4 comments on “TWiV 418: Of mice and MERS

  1. Gertrud Rey Dec 9, 2016

    I wanted to send this story to Rich, but I don’t know how to get in touch with him, so I’ll just leave it right here.