TWiV 418: Of mice and MERS

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

The TWiVsters describe a new animal model for MERS coronavirus-induced acute respiratory distress syndrome, produced by CRISPR/Cas9 editing of the mouse gene encoding an ortholog of the virus receptor.

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Links for this episode

• New mouse model for MERS (Nat Micro) 10:15
• RNA-guided genome engineering (Science) 23:50
• Photo by Finny
• Letters read on TWiV 418 3:40, 47:10

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world’s best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE. 0:25, 44:10

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Weekly Science Picks 42:25, 1:29:20

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Hannah – Bioart and Bacteria

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