CRISPR/Cas9 | This Week in Virology

Erin joins the TWiVirions to discuss a computer exploit encoded in DNA, creation of pigs free of endogenous retroviruses, and mutations in the gene encoding an innate sensor of RNA in children with severe viral respiratory disease.

TWiV 418: Of mice and MERS

December 4, 2016
Tagged as: acute respiratory disease syndrome, cell receptor, coronavirus, CRISPR/Cas9, genome editing, MERS-CoV, permissive, susceptible, viral, virology, virus, viruses

The TWiVsters describe a mouse model for MERS coronavirus-induced acute respiratory distress syndrome, produced by CRISPR/Cas9 editing of the murine gene encoding an ortholog of the virus receptor.

TWiV 411: Chicken runs

October 16, 2016
Tagged as: cell receptor, CRISPR/Cas9, Ig-like protein, live attenuated vaccine, NDV, Newcastle disease virus, norovirus, paramyxovirus, reverse spillover, viral, virology, virus, viruses, wild birds

The TWiVeroos examine a reverse spillover of Newcastle disease virus vaccines into wild birds, and identification of a protein cell receptor for murine noroviruses.

For a TWiV Thanksgiving, Vincent, Alan, and Kathy trace the feud over genome editing, a new virus discovered in human blood, and the origins of hepatitis A virus.

Tag: CRISPR/Cas9

TWiV 455: Pork and genes

TWiV 418: Of mice and MERS

TWiV 411: Chicken runs

TWiV 365: Blood, feuds, and a foodborne disease

Search

Questions or comments

Contribute

Inside a BSL-4 laboratory