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Tag: variola

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TWiV 478: A pox on your horse

  • January 28, 2018
  • Tagged as: dual use research, edward jenner, infectious DNA clone, Smallpox, smallpox vaccine, transfection, vaccinia virus, variola, viral, virology, virus, viruses

The TWiV team explains how infectious horsepox virus – likely the ancestor of smallpox vaccines – was recovered from chemically synthesized DNA fragments.

1 Reply
  • Netcast

TWiV 294: Smallpox and anthrax and flu, oh my!

  • July 20, 2014
  • Tagged as: AIDS baby, anthrax, Bacillus anthracis, BSL-3, BSL-4, cdc, H5N1, hiv, NSABB, Smallpox, variola, viral, virology, virus

The TWiV team reviews the discovery of old vials of smallpox virus at NIH, anthrax and influenza mishaps at CDC, the baby who was not cured of HIV, Cambridge Working Group, and sacking of NSABB members.

4 Replies
  • Netcast

TWiV 288: ebircsnart esreveR

  • June 8, 2014
  • Tagged as: cDNA, complementary DNA, endogenous DNA, LINE-1, mobile genetic element, non-LTR retrotransposon, reverse transcriptase, Smallpox, variola, vesicular stomatitis virus, viral, virology, virus

The Twivsters discuss how reverse transcriptase encoded in the human genome might produce DNA copies of RNA viruses in infected cells.

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