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Tag: reactivation

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TWiV 550: Covering up the shiny parts

  • June 2, 2019
  • Tagged as: antigenic hole, broadly neutralizing antibodies, epitope, herpes simplex virus, immunofocusing, latency, neuronal cell line, reactivation, universal influenza vaccine, Vaccine, viral, virology, virus, viruses

TWiV explains the use of a neuronal cell line to study herpes simplex virus latency and reactivation, and a strategy for creating vaccines that induce antibodies against specific epitopes.

3 Replies
  • Episodes
  • Netcast

TWiV 543: Stoned and senile

  • April 14, 2019
  • Tagged as: alzheimer's disease, amoebae, dementia, giant virus, herpes simplex virus 1, histone, horizontal gene transfer, Medusavirus, memory loss, mouse model, NCLDV, neurodegereration, reactivation, viral, virology, virus, viruses

The TWiV team discusses Medusavirus, isolated from a hot spring in Japan, and induction of hallmarks of neurodegeneration by recurrent herpes simplex virus 1 infection of mice.

1 Reply
  • Episodes
  • Netcast

TWiV 369: Camel runny noses and other JNK

  • December 27, 2015
  • Tagged as: camel, chromatin, coronavirus, herpes simplex virus, herpesvirus, histone, immunity, JNK, MERS, MERS-CoV, methyl/phospho switch, methylation, neuronal stress, phosphorylation, reactivation, shedding, Vaccine, viral, virology, virus, viruses
TWiV

A swarm of virologists discusses testing of a MERS coronavirus vaccine for camels, and how a neuronal stress pathway reactivates herpes simplex virus.

1 Reply
  • Netcast

TWiV 218: Monkeys turning valves and pushing buttons

  • February 3, 2013
  • Tagged as: antibody, cancer, endogenous retrovirus, erv, germline, murine leukemia virus, RAG mouse, reactivation, TLR, toll-like receptor, tumor, viral, virology, virus

Vincent, Alan, and Welkin discuss how endogenous retroviruses in mice are held in check by the immune response.

8 Replies
  • Netcast

TWiV 5: Herpesviruses

  • October 23, 2008
  • Tagged as: ganglia, herpes simplex virus, herpesvirus, latency, reactivation, Saul Silverstein, shingles, viral, virology, virus, viruses, zoster

Vincent and Saul discuss infection, latency, and reactivation by members of the herpesvirus family of viruses.

3 Replies

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