TWiV 350: Viral gene therapy with Katherine High

Katherine HighHost: Vincent Racaniello

Guest: Katherine A. High

Vincent speaks with Katherine High about her career and her work on using viral gene therapy to treat inherited disorders.

This episode is drawn from one of twenty-six video interviews with leading scientists who have made significant contributions to the field of virology, part of the new edition of the textbook Principles of Virology.

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TWiV 349: One ring to vaccinate them all

vsv plateHosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan and Rich explain how to make a functional ribosome with tethered subunits, and review the results of a phase III VSV-vectored Ebolavirus vaccine trial in Guinea.

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This episode is sponsored by ASM GAP 3:25

Timestamps by Jennifer. Thanks!

Weekly Science Picks 1:40:35

Alan – Above and Beyond
Rich – DSCOVR (Dark moon side crossing Earth)
Vincent – Stuxnet virus (Wired, YouTube)

Listener Pick of the Week

Konrad – Stated Clearly

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TWiV 348: Chicken shift

Ocular Marek's diseaseHosts: Vincent Racaniello and Rich Condit

Vincent and Rich discuss fruit fly viruses, one year without polio in Nigeria, and a permissive Marek’s disease viral vaccine that allows transmission of virulent viruses.

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This episode is sponsored by ASM GAP 7:30

Timestamps by Jennifer. Thanks!

Weekly Science Picks 1:34:00

Rich – Swan-Ganz catheter (Wiki, video)
Vincent – Mobile DNA III

Listener Pick of the Week

Kevin – Synthetic prions

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TWiV 347: Rose rosette and squirrel roulette

Rose RosetteHosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich discuss the virus behind rose rosette disease, and fatal human encephalitis caused by a variegated squirrel bornavirus.

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This episode is sponsored by ASM GAP and ICAAC/ICC

Time stamps by Jennifer. Thanks!

Weekly Science Picks 1:17:05

Alan – National Immunization Awareness Month (Twitter campaign)
Rich – Rosie Revere, Engineer by Andrea Beaty
Vincent – iPhone owns podcasts (9to5Mac)

Listener Pick of the Week

Sandra – World Zoonoses Day graphic
Peter – Mammal-carnivorous plant mutualism (bat and shrew)

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TWiV 346: A double helical career

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler

Guest: Joan Steitz

This episode was recorded at the 34th Annual Meeting of the American Society for Virology, where Vincent, Rich, and Kathy spoke with Joan Steitz, a tireless promoter of women in science and one of the greatest scientists of our generation.

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Weekly Science Picks

Kathy – Charity Hall
Rich – Ribosome binding sites of phage R17 mRNA
Vincent – Pluto flyby

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TWiV 346Photo credit: Matt Evans (click for a big view)

TWiV 345: How a vaccine got the nod

PandemrixHosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler

The TWiVonauts review how the weather affects West Nile virus disease in the US, benefit of B cell depletion for ME/CFS patients, and an autoimmune reaction induced by influenza virus vaccine that leads to narcolepsy.

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This episode is sponsored by ASM GAP – turn your science into a company

Weekly Science Picks

Dickson – Algal DMS releasing enzyme
Alan – Science of beer aging
Kathy – The Art of Science winners
Vincent – The future of Lego plastics

Listener Pick of the Week

Eric – Economics in One Lesson by Henry Hazzilit
Stephen – The Martian by Andy Weir (audiobook)

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TWiV 344: Glasgwegians go viral

Host: Vincent Racaniello

Guests: Ruth Jarrett, Glen Nemerow, and Esther Schnettler

At the Glasgow Science Festival microTALKS, Vincent speaks with Ruth, Glen, and Esther about their research on viruses and Hodgkin lymphoma, adenovirus structure and entry into cells, and interactions between arthropod borne viruses and their hosts.



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Timestamps by Jennifer. Thank you!

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TWiV 343: The silence of the turnips

Argonaute rolesHosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

The TWiVerinoes discuss the potential for prion spread by plants, global circulation patterns of influenza virus, and the roles of Argonautes and a viral protein in RNA silencing in plants.

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Timestamps by Jennifer. Thank you!

Weekly Science Picks 1:41:45

Dickson – Global rainfall and snowfall map and A Week in the Life of Rain
Alan – Automated patch clamp
Kathy – More Women in Science mini Legos
Rich – The Martian trailer
Vincent – It’s a bug’s life

Listener Pick of the Week

May – p53 by Sue Armstrong

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TWiV 342: Public epitope #1

virusesHosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

The TWiVniks discuss the structure of a virus that reproduces in an extreme environment, long-term consequences of Ebolavirus infection, and VirScan, a method to identify the different virus infections you have had in your lifetime.

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Timestamps by Jennifer. Thank you!

Weekly Science Picks 1:26:20

Dickson – Incredible photos
Alan – Alone in a room full of science writers
Kathy – Calico cats and Siamese cats
Rich – Missing link in evolution
Vincent – Podcasts saving NPR and Podcasting blossoms

Listener Pick of the Week

Jenny – What Bill Gates is afraid of
Neva – The Kardashian Index

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TWiV 341: Ebolavirus experiences

Host: Vincent Racaniello

Guests: Adam Kucharski, Gillian Slack, and Emma Thomson

Vincent returns to the University of Glasgow MRC-Center for Virus Research and speaks with Emma, Gillian, and Adam about their ebolavirus experiences: caring for an infected patient, working in an Ebola treatment center in Sierra Leone, and making epidemiological predictions about the outbreak in west Africa.



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The Hosts of TWiV

Vincent Racaniello, Ph.D.


Dickson D.
Despommier, Ph.D.


Alan Dove, Ph.D.


Daniel Griffin, M.D.,
Ph.D., CTropMed CTH


Angela Mingarelli, DVM


Jolene Ramsey, Ph.D.


CLICK FOR MORE INFO

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