TWiV 1180: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin discusses the recent increase in norovirus outbreaks, human cases of H5N1 avian influenza, before reviewing the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, how effective Molnupiravir is and provides information for Columbia University Irving Medical Center’s long COVID treatment center.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 1179: Dark matter and warning signs

TWiV reviews RFK Jr’s demand to revoke polio vaccine, Wuhan lab samples do not include close relatives to SARS-CoV-2, using artificial intelligence to discover the RNA virosphere, and biomarkers that discriminate early and late phases of respiratory virus infections from a SARS-CoV-2 human challenge study.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Angela Mingarelli

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Weekly Picks 1:32:16

Angela – Science’s 2024 breakthrough of the year, Lenacapavir  “the long shot”.  NEJM papers with Lenacapavir trials: one and two.
Kathy – Bach Toccatta and Fugue on floor piano
Rich – Never Cry Wolf
Vincent – Common Raven and American Crow

Listener Pick

Jaan – Meute (one, two, three)

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.

TWiV 1178: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin deep dives into the whooping cough epidemic and bird flu in big cats, and in conjunction with your host Vincent Racaniello discusses the recent case of paralytic poliomyelitis in Israel, measles outbreaks and HHS campaign for vaccine safety campaign before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, if the COVID mRNA vaccine is effective against symptomatic SARS-CoV-2 infection and hospitalization in children, where to find PEMGARDA, information for Columbia University Irving Medical Center’s long COVID treatment center, how long COVID effects one’s activities, personality and neuropsychiatric symptoms.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 1177: Going to school for flu

At the School for Influenza in Brisbane, TWiV speaks with Kirsty, Erik and Rebecca about their careers and their research.

Host: Vincent Racaniello

Guests: Kirsty Short, Erik Karlsson, and Rebecca Cox

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Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.

TWiV 1176: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin continues his discussion of whether the mysterious respiratory illness in the Congo is malaria, and in conjunction with your host Vincent Racaniello discusses how routine childhood immunizations especially that against poliovirus are threatened by Robert F Kennedy Jr and Aaron Siri, the origin of the SAR-CoV-2 virus and retraction of Didier Raoult’s research, then returns to discussing the first case of severe disease following H5N1 infection in humans and the state of California’s “bird flu emergency”, the benefit of the measles vaccine, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how vaccination reduced hospitalization of children between 5-17 years, the ACIP recommendation for the immunocompromised, where to find PEMGARDA, information for Columbia Unversity Irving Medical Center’s long COVID treatment center, long COVID in cancer patients and the physical malaises of long COVID.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 1175: A hitchiker’s guide to virology

TWiV reviews the appearance of poliovirus in Europe, mystery disease in DRC, global burden of Chikungunya, viruses of parasitic nematodes that induce antibody responses in vertebrate hosts, and picobirnaviruses, do they infect eukaryotes or prokaryotes?

Hosts: Vincent Racaniello, Alan Dove, and Jolene Ramsey

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Weekly Picks 1:47:58

Alan – Sondehub and radiosonde hunting
Jolene – Book “10 to 25: The Science of Motivating Young People” By David Yeager
Vincent – Dr. Vinay Prasad “Sabotaging RFK Jr’s Confirmation Will Increase Vaccine Hesitancy” & “Doctors Criticizing RFK Jr. Paved the Way for His Ascendancy”

Listener Picks

Syl – Foldscope
Jennifer – minutiae

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.

TWiV 1174: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin deep dives into whether the mysterious respiratory illness in the Congo is malaria, and in conjunction with your host Vincent Racaniello discusses the failure of the poliovirus eradication campaign with virus circulation detected throughout Europe and how we should focus on disease control not virus circulation, then returns to discussing avian influenza in raw milk and the early stoppage of the mpox antiviral Tecovirimat  before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, if there is a difference in protection against the development of severe disease between an mRNA or a protein based vaccine, where to find PEMGARDA, and information for Columbia Unversity Irving Medical Center’s long COVID treatment center.

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  • Is the mysterious disease in the Congo, malaria? (AP News) 5:05
  • State of global health, year-end remarks by WHO director-general (WHO)
  • Really, progress towards poliomyelitis eradication? (CDC MMWR) 7:47
  • Increases in confirm cases ¹ control of poliomyelitis (WHO) 9:10
  • Polio European Union and United Kingdom, is that 1 global entry? (Science) 10:41
  • Is the WHO the global CDC?  polio vaccination guidelines (WHO) 14:41
  • Do you feed your cats raw milk? (Public Health LA county) 16:39
  • Is there avian influenza in the zoo near you? (Maricopa) 17:32
  • Don’t feed your cat raw milk (CIDRAP)
  • Holy Cow! H5N1 in cows! (microbeTV) 18:20
  • Tecovirimat no improvement in Mpox resolution or pain (NIAID NIH) 18:52
  • Interim results from STOMP study of  Tecovirimat (SIGA) 19:18
  • Trial stops enrollment after Tpoxx fails (CIDRAP) 1918
  • Is Tecovirimat really first-in-class mpox therapy? (Viruses)
  • Influenza weekly surveillance report: clift notes (CDC FluView) 21:03
  • US respiratory virus activity (CDC Respiratory Illnesses) 21:03
  • Waste water scan for 11 pathogens (WastewaterSCan) 21;56
  • RSV-Network (CDC Respiratory Syncytial virus Infection) 22:25
  • COVID-19 deaths (CDC)
  • COVID-19 national and regional trends (CDC) 23:20
  • Waste water scan for 11 pathogens (WastewaterSCan) 23:28
  • COVID-19 variant tracker (CDC)
  • SARS-CoV-2 genomes galore (Nextstrain)
  • Relative effectiveness of homologous NVX-CoV2373 and BNT162b2 COVID-19 vaccinations in South Korea (Vaccine) 24:46
  • Phase III trial results! Comparative efficacy and safety of COVID-19 (BMC Infectious Diseases) 26:23
  • Where to get pemgarda (Pemgarda)
  • EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
  • Fusion center near you….if in NY (Prime Fusions)
  • CDC Quarantine guidelines (CDC)
  • NIH COVID-19 treatment guidelines (NIH)
  • Infectious Disease Society guidelines for treatment and management (ID Society)
  • Drug interaction checker (University of Liverpool)
  • Molnupiravir safety and efficacy (JMV)
  • Convalescent plasma recommendation for immunocompromised (ID Society)
  • What to do when sick with a respiratory virus (CDC)
  • When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
  • Managing healthcare staffing shortages (CDC)
  • Stop playing favorites with COVID-19 in healthcare settings (Infection Control & Hospital Epidemiology) 27:51
  • Steroids, dexamethasone at the right time (OFID)
  • Anticoagulation guidelines (hematology.org)
  • Remdesivir Effectiveness in Reducing the Risk of 30-day Readmission in Vulnerable Patients Hospitalized for COVID-19 (CID)
  • Daniel Griffin’s evidence based medical practices for long COVID (OFID)
  • Long COVID hotline (Columbia : Columbia University Irving Medical Center)
  • Letters read on TWiV 1174 35:13
  • Dr. Griffin’s COVID treatment summary (pdf)
  • Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 1173: Holy Cow! Convergent evolution!

TWiV reviews nominees to head NIH, FDA, and CDC, cervical cancer decline following HPV vaccination, local dengue in Texas, human isolate of H5N1 virus is transmissible and virulent in animal models, and shared mechanisms of immune evasion among animal and bacterial viruses.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey

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Weekly Picks 1:32:28

Brianne – Pale Blue Pod
Kathy – PhysicsGirl recent Instagram post, ScienceAdvisor signup free daily sci news distillation, Semi-conducting hydrogels, Bot that can pick up things with a soft touch, “Pigeonbot II”, a drone called LisRaptor, zapping forever chemicals like PFAS with light and here
Rich – Vendee Globe
Jolene – Center for the Improvement of Mentored Research Experiences
Vincent – These two ancient human relatives crossed paths 1.5 million years ago

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.

TWiV 1172: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin summarizes influenza and RSV circulation in the US, the benefit of administering oseltamivir early and if influenza vaccination reduces secondary household infections, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how 1st or 2nd trimester SARS-CoV-2 infections may shorten newborn telomeres, what are B1 cells, if IgG4 responses are critical for protection elicited by mRNA vaccines, if there is a difference in protection against the development of severe disease between an mRNA or a protein based vaccine, where to find PEMGARDA, if remdesivir reduces readmission of vulnerable patients once hospitalized for COVID-19, information for Columbia University Irving Medical Center’s long COVID treatment center, if transcutaneous electrical nerve stimulation ameliorates musculoskeletal pain and fatigue during long COVID, do antihistamines reduce post-acute sequelae of SARS-CoV-2 infection and how long can SARS-CoV-2 antigens be detected in blood.

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  • Influenza weekly surveillance report: cliff notes (CDC FluView) 1:59
  • US respiratory virus activity (CDC Respiratory Illnesses) 1:59
  • Influenza vaccines protect against secondary infections in households (JAMA Network) 2:58
  • Benefit of early oseltamivir therapy for influenza A (CID) 4:30
  • RSV-Network (CDC Respiratory Syncytial virus Infection) 6:36
  • COVID-19 deaths (CDC) 6:56
  • COVID-19 national and regional trends (CDC) 7:03
  • Waste water scan for 11 pathogens (WastewaterSCan) 7:15
  • COVID-19 variant tracker (CDC)
  • SARS-CoV-2 genomes galore (Nextstrain)
  • Maternal infection of SARS-CoV-2 during 1st and 2nd trimesters newborn telomere shortening (Journal of Translational Medicine) 7:35
  • What is a B1 cell? (Wikipedia) 9:13
  • Pre-COVID and post-COVID vaccination on long COVID (Journal of Infection) 11:45
  • Delayed Induction of Noninflammatory SARS-CoV-2 Spike-Specific IgG4 Antibodies after  BNT162b2 Vaccination in Children (The Pediatric Infectious Disease Journal) 15:45
  • Relative effectiveness of homologous NVX-CoV2373 and BNT162b2 COVID-19 vaccinations in South Korea (Vaccine) 18:22
  • Phase III trial results! Comparative efficacy and safety of COVID-19 vaccines (BMC Infectious Diseases) 19:35
  • Where to get pemgarda (Pemgarda)
  • EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
  • Fusion center near you….if in NY (Prime Fusions)
  • CDC Quarantine guidelines (CDC)
  • NIH COVID-19 treatment guidelines (NIH)
  • Infectious Disease Society guidelines for treatment and management (ID Society)
  • Drug interaction checker (University of Liverpool)
  • Molnupiravir safety and efficacy (JMV)
  • Convalescent plasma recommendation for immunocompromised (ID Society)
  • What to do when sick with a respiratory virus (CDC)
  • When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
  • Managing healthcare staffing shortages (CDC)
  • Steroids, dexamethasone at the right time (OFID)
  • Anticoagulation guidelines (hematology.org)
  • Remdesivir Effectiveness in Reducing the Risk of 30-day Readmission in Vulnerable Patients Hospitalized for COVID-19 (CID) 21:06
  • Daniel Griffin’s evidence based medical practices for long COVID (OFID) 22:23
  • Long COVID hotline (Columbia : Columbia University Irving Medical Center) 22:30
  • Transcutaneous electrical nerve stimulation for fibromyalgia-like syndrome in patients with Long-COVID(Scientific Reports) 22:55
  • Mitigating the risks of post-acute sequelae of SARS-CoV-2 infection (PASC) with intranasal chlorpheniramine (BMC Infectious Diseases) 26:15
  • Measurement of circulating viral antigens post-SARS-CoV-2 infection (CID) 27:40
  • Letters read on TWiV 1172 31:30
  • Dr. Griffin’s COVID treatment summary (pdf)
  • Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 1171: The born immunity

TWiV reviews susceptibility to vaccine-preventable infections in asylum seekers, the economic power of vaccines, French university tries to bury its investigation of a faculty member’s ethical lapses, transmission dynamics of SARS-CoV-2 in New Zealand before and after COVID-19, and a germ line encoded antibody that recognizes a broad array of enveloped viruses.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker

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Weekly Picks 1:29:20

Brianne – Publication of Updated Human Cell Atlas
Rich – Astroscale
Alan – E3 ubiquitin ligase game, and an article about its origin
Vincent – In the Quantum World, Even Points of View Are Uncertain

Listener Pick

Ryan – A Dangerous Moment

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.

The Hosts of TWiV

Vincent Racaniello, Ph.D.


Brianne Barker, Ph.D.


Rich Condit, Ph.D.


Alan Dove, Ph.D.


Daniel Griffin, M.D.,
Ph.D., CTropMed CTH


Angela Mingarelli, DVM


Jolene Ramsey, Ph.D.


Kathy Spindler, Ph.D.


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