TWiV 1190: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss changes in access to public health information and aid mechanisms such as the return of MMWR, the largest tuberculosis outbreak in the US ever, lack of USAID in fighting Marburg and Ebola outbreaks in Africa, discussing if avian influenza virus is airborne, how eggs are effected and the emergence of second spillover into dairy cattle, how the difference between nOPV2 and Sabin OPV2 is a minor reduction in the association of vaccine associated paralytic poliomyelitis before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, how children may be affected by long COVID and if SARS-CoV-2 and other inflammatory syndromes increase the risk of Alzheimer’s disease.

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  • The return of MMWR (CDC) 00:50
  • Largest tuberculosis outbreak ever in the US (Kansas Department of Health and Environment) 2:33
  • Marburg virus outbreak in Tanzania (Doctors without borders) 4:26
  • No USAID, Ebola outbreak in Uganda spreads (CBS News) 5:44
  • WHO accelerates efforts to Ebola response in Uganda (WHO: Uganda) 6:26
  • Global partners enable access to vaccine and treatment for Ebola outbreak in Uganda (WHO) 6:26
  • Ventilation and respiratory viruses (CDC National Institute for Occupational safety and health)
  • Is bird flu flying through the air…..is the virus literally airborne? (NY Times) 8:51
  • Is bird flu like measles (American Journal of Epidemiology)
  • Indoor safety guideline (Herokuapp)
  • Dairy herds in Nevada have influenza! (CIDRAP) 15:46
  • Do your eggs have H5N1? (NY Times) 17:05
  • New genotye D1.1 of avian flu in dairy cattle(USDA Animal and Plant Health Inspection Service) 17:47
  • Second spillover of avian flu into dairy cattle….does this story sound familiar? (CIDRAP) 17:47
  • Impact of using nOPV2 in mass vaccination campaigns? (JID) 19:22
  • Waste water scan for 11 pathogens (WastewaterSCan)
  • US respiratory virus activity (CDC Respiratory Illnesses) 24:12
  • Weekly surveillance report: clift notes (CDC FluView) 24:12
  • As flu increases so do deaths in kids (CIDRAP) 24:30
  • People most impacted by respiratory viruses (CDC)
  • Co-infection with SARS-CoV-2 and influenza A/B (BMC Infectious Diseases) 24:51
  • Oseltamivir reduces 30-Day mortality in older adults with Influenza (OFID) 25:13
  • RSV: Waste water scan for 11 pathogens (WastewaterSCan) 27:53
  • RSV-Network (CDC Respiratory Syncytial virus Infection) 27:53
  • US respiratory virus activity (CDC Respiratory Illnesses) 27:53
  • Waste water scan for 11 pathogens (WastewaterSCan) 29:40
  • COVID-19 deaths (CDC) 29:01
  • COVID-19 national and regional trends (CDC) 29:01
  • COVID-19 variant tracker (CDC)
  • SARS-CoV-2 genomes galore (Nextstrain)
  • Where to get pemgarda (Pemgarda)
  • EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
  • Fusion center near you….if in NY (Prime Fusions)
  • CDC Quarantine guidelines (CDC)
  • NIH COVID-19 treatment guidelines (NIH)
  • Drug interaction checker (University of Liverpool)
  • Paxlovid update (Pfizer) 30:23
  • Infectious Disease Society guidelines for treatment and management (ID Society)
  • Molnupiravir safety and efficacy (JMV)
  • Convalescent plasma recommendation for immunocompromised (ID Society)
  • What to do when sick with a respiratory virus (CDC)
  • When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
  • Managing healthcare staffing shortages (CDC)
  • Steroids, dexamethasone at the right time (OFID)
  • Anticoagulation guidelines (hematology.org)
  • Daniel Griffin’s evidence based medical practices for long COVID (OFID)
  • Long COVID hotline (Columbia : Columbia University Irving Medical Center)
  • The answers: Long COVID
  • Long COVID Recovery Program with Zara Dureno, BA, MOT
  • Long COVID pevalence and associated activity limitation in US children
  • (JAMA Pediatrics) 32:10
  • Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection (Nature Medicine) 33:40
  • Letters read on TWiV 1190 38:33
  • Dr. Griffin’s COVID treatment summary (pdf)
  • Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 1189: Viruses making waves

TWiV notes the HHS communication pause, and describes research showing that rotavirus viroporin activity is necessary for intracellular calcium signals that contribute to viral pathogenesis, and control of human orthrflavivirus vaccine challenge by T cells in the absence of neutralizing antibodies.

Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker

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Weekly Picks 1:17:35

Brianne – The Perfect Cacio e Pepe Recipe, According to Science (primary article here)
Kathy – Dragonflies Loop-the-Loop
Alan – My Beloved Monster, by Caleb Carr
Vincent –  Why Did the FDA Ban Red Dye #3

Listener Picks

Anne – Japan’s 65-Foot Towering Snow Walls

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.

TWiV 1188: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss changes in access to public health information, the Marburg and Ebola outbreaks in Africa, the largest tuberculosis outbreak in the US ever, the politicization of polio vaccine campaigns in Pakistan, effect of high pathogenic influenza in animals and on the economy before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, trials and devices to relieve some neurological complications of long COVID and the ramifications of long COVID in children, healthcare workers and adults. 

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 1187: The tau of herpesvirus

TWiV explains a new blood test for head and neck cancer, Japanese regulators approve tecovirimat for mpox, an entry receptor for enterovirus D68, and anti-herpetic tau preserves neurons via a DNA sensing pathway in Alzheimer’s disease.

Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, Brianne Barker, and Angela Mingarelli

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Weekly Picks 1:36:38

Angela – Good genes are nice, but joy is better
Brianne – Beaker Hair Clip
Kathy – Pareidolia explained by street artist David Zinn TEDx talk   Also visit zinnart.com
Alan – Screwworm is coming back in the Americas
Vincent –  Dr. Jay Bhattacharya Was Nice to Someone During a Debate. That Doesn’t Erase the Consequences of His Misinformation

Listener Picks

Sarah – The Extremophile Campaign: In Your Home  (ECIYH) citizen science

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.

TWiV 1186: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and co-host Vincent Racaniello lament about the public changes from withdrawing from the WHO to health and scientific communication pauses by the Trump Administration after a brief discussion of Marburg in Tanzania and mpox in England before reviewing cats and bird flu, the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, and where to go for answers to your long COVID questions.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 1185: The birds and the Bs

TWiV explains Guillain-Barré Syndrome associated with RSV vaccines, outbreaks of metapneumovirus in China and India, editors resign to protest Elsevier’s use of AI in publishing, global distribution and diversity of wild bird associated pathogens, and broadly inhibitory anti-neuraminidase antibody from human memory B cells.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker

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Weekly Picks 1:36:51

Brianne – Dear Reviewer 2
Rich – National Data Buoy Center
Alan – BBC audio program on the World Morse Code Championships
Vincent – These are the 20 most-studied bacteria — the majority have been ignored

Listener Picks

Peter – Local graffiti in Sydney
Vivian – The Peoples’ Hospital by Dr. Ricardo Nuila

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.

TWiV 1184: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin discusses current and past outbreaks of “vaccine” preventable diseases including whooping cough, polio and measles with your co-host Vincent Racaniello and the recent increase in norovirus outbreaks, if alcohol-based hand sanitizers aid in the spread of norovirus before reviewing the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, if “long COVID” like symptoms occurs after influenza and how long COVID may associate with neurological complicates that control verbal memory.

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  • Notable infectious diseases in US (CDC NNDSS)
  • Get your Tdap: whooping cough case increase (California Department of Public Health) 2:22
  • Resurgence of measles among preschool aged children 1989-1991 (CDC: MMWR) 3:08
  • Adults vulnerable to ‘childhood’ diseases  (NY Times) 2:04
  • Pivotal decision that led to a resurgence of polio (NY Times) 3:31
  • Can polio return due to lagging vaccination? (NY Times) 3:31
  • NoroSTAT Data Table (CDC Norovirus)
  • The discovery of the 27-nm Norwalk virus: an historic perspective (JID) 12:05
  • Why the “Ferrari of viruses” is surging through the northern hemisphere (Science) 10:36
  • Waste water scan for 11 pathogens (WastewaterSCan)
  • Norovirus at Chipotle, $25 million food fine (NY Times)
  • Chipotle food issues: 2015 settlement with the justice department  (Chipotle News)
  • Purcel anyone? Hand sanitizers increase norovirus risk? (Canadian Medical Association Journal) 20:10
  • Visualization by immune electron microscopy of a 27nm particle associated with acute infectious nonbacterial gastroenteritis (Journal of Virology)
  • Winter vomiting disease (JID) 15:21
  • ACIP: expanded recommendations for pneumococcal conjugate vaccines(CDC: MMWR) 20:00
  • Presumptive bird flu case in San Francisco (SF. Gov) 22:18
  • Waste water scan for 11 pathogens (WastewaterSCan)
  • US respiratory virus activity (CDC Respiratory Illnesses) 23:03
  • Weekly surveillance report: cliff notes (CDC FluView)
  • Antiviral medications for treatment of nonsevere influenza (JAMA Network: JAMA Internal Medicine) 23:58
  •  Xofluza (GoodRx) 23:52
  • RSV: Waste water scan for 11 pathogens (WastewaterSCan)
  • RSV-Network (CDC Respiratory Syncytial virus Infection) 30:07
  • US respiratory virus activity (CDC Respiratory Illnesses)
  • Waste water scan for 11 pathogens (WastewaterSCan)
  • COVID-19 deaths (CDC)
  • COVID-19 national and regional trends (CDC) 30:41
  • COVID-19 variant tracker (CDC)
  • SARS-CoV-2 genomes galore (Nextstrain)
  • Where to get pemgarda (Pemgarda)
  • EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
  • Fusion center near you….if in NY (Prime Fusions)
  • CDC Quarantine guidelines (CDC)
  • NIH COVID-19 treatment guidelines (NIH)
  • Infectious Disease Society guidelines for treatment and management (ID Society)
  • Drug interaction checker (University of Liverpool)
  • Molnupiravir safety and efficacy (JMV)
  • Convalescent plasma recommendation for immunocompromised (ID Society)
  • What to do when sick with a respiratory virus (CDC)
  • When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
  • Managing healthcare staffing shortages (CDC)
  • Steroids, dexamethasone at the right time (OFID)
  • Anticoagulation guidelines (hematology.org)
  • Daniel Griffin’s evidence based medical practices for long COVID (OFID)
  • Long COVID hotline (Columbia : Columbia University Irving Medical Center)
  • Symptom evolution in individuals with ongoing symptomatic COVID-19 and post COVID-19 syndrome after SARS-CoV-2 vaccination versus influenza vccination (Journal of Infection) 32:16
  • Neurological post-COVID syndrome is associated with substantial impairment of verbal short-term and working memory (Scientific Reports) 34:53
  • Letters read on TWiV 1184 36:36
  • Dr. Griffin’s COVID treatment summary (pdf)
  • Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 1183: More than 2024 viruses

TWiV reviews some of their favorite virology stories from 2024.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

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Weekly Picks 1:32:20

Brianne – Scientists put vampire bats on treadmills to learn about metabolism
Kathy – Says Who?: A Kinder, Funner, Usage Guide for Everyone Who Cares About Words
Rich – Mark Rober on PBS Newshour Brief But Spectacular (Wiki; Testing The World’s Smartest Crow)
Vincent – How Glenn Gould Broke Classical Music

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.

TWiV 1182: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin discusses how vaccination and vaccine hesitancy affects public health and disease spread in terms of mpox, the first human death from H5N1 in US, why one should not feed their pets raw pet food and the metapneumonia outbreak in China before reviewing the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, how nirmatrelvir-ritonavir/Paxlovid reduces adverse outcomes of COVID in patients with kidney disease, provides information for Columbia University Irving Medical Center’s long COVID treatment center, SARS-CoV-2 infection affects skin conditions including shingles and if long antiviral treatment affects long COVID.

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  • Mpox vaccination hesitancy, previous immunisation coverage, and vaccination readiness in the African region (eClincial Medicine) 3:04
  • Global prevalence and correlates of mpox vaccine acceptance and uptake (Communications Medicine) 3:15
  • First case of new mpox variant in France (Reuters) 4:05
  • First “Bird flu” death in US (NY Times) 4:51
  • Emerging threat of H5N1 to human health (NEJM)
  • Don’t feed your pets raw food (County of Los Angeles Public Health) 7:23
  • Oregon, nationwide raw pet food recall (CIDRAP) 7:48
  • Raw cat food avian flu, is this like raw milk? (CIDRAP) 6:55
  • Human metapneumovirus surging in China (The Guardian) 9:38
  • Viral video of viral chaos: human metapneumovirus in Chinese hospital (The Economic Times) 9:48
  • Human metapneumovirus in China (NY Times) 10:00
  • Acute respiratory infections including human metapneumovirus in northern hemisphere (WHO) 10:43
  • Waste water scan for 11 pathogens (WastewaterSCan) 13:28
  • US respiratory virus activity (CDC Respiratory Illnesses) 12:40
  • Weekly surveillance report: clift notes (CDC FluView)
  • RSV: Waste water scan for 11 pathogens (WastewaterSCan)
  • RSV-Network (CDC Respiratory Syncytial virus Infection)
  • US respiratory virus activity (CDC Respiratory Illnesses) 13:12
  • Waste water scan for 11 pathogens (WastewaterSCan) 13:23
  • COVID-19 deaths (CDC)
  • COVID-19 national and regional trends (CDC)
  • COVID-19 variant tracker (CDC)
  • SARS-CoV-2 genomes galore (Nextstrain)
  • Where to get pemgarda (Pemgarda)
  • EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
  • Fusion center near you….if in NY (Prime Fusions)
  • CDC Quarantine guidelines (CDC)
  • NIH COVID-19 treatment guidelines (NIH)
  • Infectious Disease Society guidelines for treatment and management (ID Society)
  • Drug interaction checker (University of Liverpool)
  • The effect of nirmatrelvir-ritonavir on short- and long-term adverse outcomes from COVID-19 among patients with kidney disease (OFID) 14:35
  • Paxlovid tied to lower risk of hospital stay, heart problems, death in adults with kidney disease and COVID (CIDRAP) 16:09
  • Molnupiravir safety and efficacy (JMV)
  • Convalescent plasma recommendation for immunocompromised (ID Society)
  • What to do when sick with a respiratory virus (CDC)
  • When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
  • Managing healthcare staffing shortages (CDC)
  • Steroids, dexamethasone at the right time (OFID)
  • Anticoagulation guidelines (hematology.org)
  • Daniel Griffin’s evidence based medical practices for long COVID (OFID)
  • Long COVID hotline (Columbia : Columbia University Irving Medical Center)
  • Chronic urticaria, vitiligo, alopecia areata, and herpes zoster following COVID-19 infection (Journal of Dermatology) 18:02
  • Impact of extended-course oral nirmatrelvir/ritonavir in established Long COVID:
  • (Communications Medicine) 19:50
  • Letters read on TWiV 1182 22:18
  • Dr. Griffin’s COVID treatment summary (pdf)
  • Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 1181: Seek and ye shall find, coronaviruses and phage

TWiV discusses an outbreak of influenza H5N1 that killed over half of the great cats at a Washington sanctuary, origin and cross-species transmission of bat coronaviruses in China, and the diverse and abundant phages that enter cells via receptors encoded on conjugative plasmids.

Hosts: Vincent Racaniello, Rich Condit, and Jolene Ramsey

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Weekly Picks 1:34:24

Rich – Pareidolia (wiki)
Jolene – Pathways to Science database
Vincent – Wendy Carlos and Switched-On Bach

Listener Picks

Arjan – Gutsick Gibbon’s YouTube channel
Alan – 2024 Nobel Prize Lectures in Chemistry

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.

The Hosts of TWiV

Vincent Racaniello, Ph.D.


Brianne Barker, Ph.D.


Rich Condit, Ph.D.


Alan Dove, Ph.D.


Daniel Griffin, M.D.,
Ph.D., CTropMed CTH


Angela Mingarelli, DVM


Jolene Ramsey, Ph.D.


Kathy Spindler, Ph.D.


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