The entire TWiV team comes together to pay tribute to Dickson Despommier, then reviews antibodies to H5N1 virus in veterinarians working with dairy cattle, Elisabeth Bik donates prize money for data integrity analyses, measles outbreak in Texas, and use of an alternative genetic code by human microbiome phages.
In his weekly clinical update, Dr. Griffin and Vincent Racaniello reminiscence about Dickson before discussing discharging Ebola patients, another announcement of emergency measures to control polio spread and the third nOPV2 vaccination campaign in Gaza in less than 6 months, the measles outbreak in the US, vaccination campaign for chickens against high pathogenic avian flu before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center’s long COVID treatment center, and where to go for answers to your long COVID questions.
A randomized, double-blind, Phase 1, single- and multiple-dose placebo-controlled study of the safety and pharmacokinetics of IN-006, an inhaled antibody treatment for COVID-19 in healthy volunteers (eBioMedicine) 38:59
Ensitrelvirfor the Treatment of Nonhospitalized Adults with COVID-19 (CID) 41:51
TWiV reviews a facility accident that killed monkeys, new bird blu genotype found in Nevada dairy cattle, Argentina plans to leave WHO, yellow fever on the rise, dynamics of HPV infections in women, and Epstein-Barr virus protein targets B cell receptor for degradation.
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss confirmation of Robert F Kennedy as HHS sectary, mpox, Ebola, how the American people support vaccine development and administration, the measles outbreak in the US-Texas, Georgia and influenza: the number of human infections, high avian flu in mammals, house cats and dairy cows before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, how long COVID varies between children and adults and if viral infection reduces telomere length in sperm.
TWiV reviews freezes and unfreezes of US government grants, how prior COVID-19 vaccination prevents over-reaction of the innate immune response during infections, and how bat genomes illuminate adaptations to viral tolerance and disease resistance.
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss changes in access to public health information and aid mechanisms such as the return of MMWR, the largest tuberculosis outbreak in the US ever, lack of USAID in fighting Marburg and Ebola outbreaks in Africa, discussing if avian influenza virus is airborne, how eggs are effected and the emergence of second spillover into dairy cattle, how the difference between nOPV2 and Sabin OPV2 is a minor reduction in the association of vaccine associated paralytic poliomyelitis before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, how children may be affected by long COVID and if SARS-CoV-2 and other inflammatory syndromes increase the risk of Alzheimer’s disease.
TWiV notes the HHS communication pause, and describes research showing that rotavirus viroporin activity is necessary for intracellular calcium signals that contribute to viral pathogenesis, and control of human orthrflavivirus vaccine challenge by T cells in the absence of neutralizing antibodies.
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss changes in access to public health information, the Marburg and Ebola outbreaks in Africa, the largest tuberculosis outbreak in the US ever, the politicization of polio vaccine campaigns in Pakistan, effect of high pathogenic influenza in animals and on the economy before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, trials and devices to relieve some neurological complications of long COVID and the ramifications of long COVID in children, healthcare workers and adults.
Distinct pro-inflammatory/pro-angiogenetic signatures distinguish children with Long COVID from controls (Pediatric Research) 31:40
Persistent symptoms and clinical findings in adults with post-acute sequelae of COVID-19/post-COVID-19 syndrome in the second year after acute infection (PLoS Medicine) 33:36
SARS-COV-2 re-infection and incidence of post-acute sequelae of COVID-19 (PASC) among essential workers in New York (LANCET: Regional Health Americas) 34:38
Impact of COVID-19 Pandemic on the incidence and prevalence of postural orthostatictachycardia syndrome(EHJ-QCCO European Heart Journal-Quality of Care & Clinical Outcomes) 36:20
TWiV explains a new blood test for head and neck cancer, Japanese regulators approve tecovirimat for mpox, an entry receptor for enterovirus D68, and anti-herpetic tau preserves neurons via a DNA sensing pathway in Alzheimer’s disease.
In his weekly clinical update, Dr. Griffin and co-host Vincent Racaniello lament about the public changes from withdrawing from the WHO to health and scientific communication pauses by the Trump Administration after a brief discussion of Marburg in Tanzania and mpox in England before reviewing cats and bird flu, the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, and where to go for answers to your long COVID questions.
Comparative effectivenessof baloxavir marboxil and oseltamir treatment for reducing household transmission of influenza (Influenza and other respiratory viruses) 16:56
RSV: Waste water scan for 11 pathogens (WastewaterSCan) 21:34
Drug interaction checker (University of Liverpool)
Real‐world effectiveness and safety of oral azvudine versus nirmatrelvir‒ritonavir (Paxlovid) in hospitalized patients with COVID-19(Signal Transduction and Targeted Therapy) 26:50
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