In his weekly clinical update, Dr. Griffin discusses how vaccination and vaccine hesitancy affects public health and disease spread in terms of mpox, the first human death from H5N1 in US, why one should not feed their pets raw pet food and the metapneumonia outbreak in China before reviewing the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, how nirmatrelvir-ritonavir/Paxlovid reduces adverse outcomes of COVID in patients with kidney disease, provides information for Columbia University Irving Medical Center’s long COVID treatment center, SARS-CoV-2 infection affects skin conditions including shingles and if long antiviral treatment affects long COVID.

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  • Mpox vaccination hesitancy, previous immunisation coverage, and vaccination readiness in the African region (eClincial Medicine) 3:04
  • Global prevalence and correlates of mpox vaccine acceptance and uptake (Communications Medicine) 3:15
  • First case of new mpox variant in France (Reuters) 4:05
  • First “Bird flu” death in US (NY Times) 4:51
  • Emerging threat of H5N1 to human health (NEJM)
  • Don’t feed your pets raw food (County of Los Angeles Public Health) 7:23
  • Oregon, nationwide raw pet food recall (CIDRAP) 7:48
  • Raw cat food avian flu, is this like raw milk? (CIDRAP) 6:55
  • Human metapneumovirus surging in China (The Guardian) 9:38
  • Viral video of viral chaos: human metapneumovirus in Chinese hospital (The Economic Times) 9:48
  • Human metapneumovirus in China (NY Times) 10:00
  • Acute respiratory infections including human metapneumovirus in northern hemisphere (WHO) 10:43
  • Waste water scan for 11 pathogens (WastewaterSCan) 13:28
  • US respiratory virus activity (CDC Respiratory Illnesses) 12:40
  • Weekly surveillance report: clift notes (CDC FluView)
  • RSV: Waste water scan for 11 pathogens (WastewaterSCan)
  • RSV-Network (CDC Respiratory Syncytial virus Infection)
  • US respiratory virus activity (CDC Respiratory Illnesses) 13:12
  • Waste water scan for 11 pathogens (WastewaterSCan) 13:23
  • COVID-19 deaths (CDC)
  • COVID-19 national and regional trends (CDC)
  • COVID-19 variant tracker (CDC)
  • SARS-CoV-2 genomes galore (Nextstrain)
  • Where to get pemgarda (Pemgarda)
  • EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
  • Fusion center near you….if in NY (Prime Fusions)
  • CDC Quarantine guidelines (CDC)
  • NIH COVID-19 treatment guidelines (NIH)
  • Infectious Disease Society guidelines for treatment and management (ID Society)
  • Drug interaction checker (University of Liverpool)
  • The effect of nirmatrelvir-ritonavir on short- and long-term adverse outcomes from COVID-19 among patients with kidney disease (OFID) 14:35
  • Paxlovid tied to lower risk of hospital stay, heart problems, death in adults with kidney disease and COVID (CIDRAP) 16:09
  • Molnupiravir safety and efficacy (JMV)
  • Convalescent plasma recommendation for immunocompromised (ID Society)
  • What to do when sick with a respiratory virus (CDC)
  • When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
  • Managing healthcare staffing shortages (CDC)
  • Steroids, dexamethasone at the right time (OFID)
  • Anticoagulation guidelines (hematology.org)
  • Daniel Griffin’s evidence based medical practices for long COVID (OFID)
  • Long COVID hotline (Columbia : Columbia University Irving Medical Center)
  • Chronic urticaria, vitiligo, alopecia areata, and herpes zoster following COVID-19 infection (Journal of Dermatology) 18:02
  • Impact of extended-course oral nirmatrelvir/ritonavir in established Long COVID:
  • (Communications Medicine) 19:50
  • Letters read on TWiV 1182 22:18
  • Dr. Griffin’s COVID treatment summary (pdf)
  • Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV discusses an outbreak of influenza H5N1 that killed over half of the great cats at a Washington sanctuary, origin and cross-species transmission of bat coronaviruses in China, and the diverse and abundant phages that enter cells via receptors encoded on conjugative plasmids.

Hosts: Vincent Racaniello, Rich Condit, and Jolene Ramsey

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Weekly Picks 1:34:24

RichPareidolia (wiki)
JolenePathways to Science database
VincentWendy Carlos and Switched-On Bach

Listener Picks

ArjanGutsick Gibbon’s YouTube channel
Alan2024 Nobel Prize Lectures in Chemistry

Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin discusses the recent increase in norovirus outbreaks, human cases of H5N1 avian influenza, before reviewing the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, how effective Molnupiravir is and provides information for Columbia University Irving Medical Center’s long COVID treatment center.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV reviews RFK Jr’s demand to revoke polio vaccine, Wuhan lab samples do not include close relatives to SARS-CoV-2, using artificial intelligence to discover the RNA virosphere, and biomarkers that discriminate early and late phases of respiratory virus infections from a SARS-CoV-2 human challenge study.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Angela Mingarelli

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Weekly Picks 1:32:16

AngelaScience’s 2024 breakthrough of the year, Lenacapavir  “the long shot”.  NEJM papers with Lenacapavir trials: one and two.
KathyBach Toccatta and Fugue on floor piano
RichNever Cry Wolf
VincentCommon Raven and American Crow

Listener Pick

Jaan – Meute (one, two, three)

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin deep dives into the whooping cough epidemic and bird flu in big cats, and in conjunction with your host Vincent Racaniello discusses the recent case of paralytic poliomyelitis in Israel, measles outbreaks and HHS campaign for vaccine safety campaign before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, if the COVID mRNA vaccine is effective against symptomatic SARS-CoV-2 infection and hospitalization in children, where to find PEMGARDA, information for Columbia University Irving Medical Center’s long COVID treatment center, how long COVID effects one’s activities, personality and neuropsychiatric symptoms.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

At the School for Influenza in Brisbane, TWiV speaks with Kirsty, Erik and Rebecca about their careers and their research.

Host: Vincent Racaniello

Guests: Kirsty Short, Erik Karlsson, and Rebecca Cox

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Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin continues his discussion of whether the mysterious respiratory illness in the Congo is malaria, and in conjunction with your host Vincent Racaniello discusses how routine childhood immunizations especially that against poliovirus are threatened by Robert F Kennedy Jr and Aaron Siri, the origin of the SAR-CoV-2 virus and retraction of Didier Raoult’s research, then returns to discussing the first case of severe disease following H5N1 infection in humans and the state of California’s “bird flu emergency”, the benefit of the measles vaccine, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how vaccination reduced hospitalization of children between 5-17 years, the ACIP recommendation for the immunocompromised, where to find PEMGARDA, information for Columbia Unversity Irving Medical Center’s long COVID treatment center, long COVID in cancer patients and the physical malaises of long COVID.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV reviews the appearance of poliovirus in Europe, mystery disease in DRC, global burden of Chikungunya, viruses of parasitic nematodes that induce antibody responses in vertebrate hosts, and picobirnaviruses, do they infect eukaryotes or prokaryotes?

Hosts: Vincent Racaniello, Alan Dove, and Jolene Ramsey

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Weekly Picks 1:47:58

AlanSondehub and radiosonde hunting
Jolene Book “10 to 25: The Science of Motivating Young PeopleBy David Yeager
VincentDr. Vinay Prasad “Sabotaging RFK Jr’s Confirmation Will Increase Vaccine Hesitancy” & “Doctors Criticizing RFK Jr. Paved the Way for His Ascendancy”

Listener Picks

SylFoldscope
Jenniferminutiae

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin deep dives into whether the mysterious respiratory illness in the Congo is malaria, and in conjunction with your host Vincent Racaniello discusses the failure of the poliovirus eradication campaign with virus circulation detected throughout Europe and how we should focus on disease control not virus circulation, then returns to discussing avian influenza in raw milk and the early stoppage of the mpox antiviral Tecovirimat  before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, if there is a difference in protection against the development of severe disease between an mRNA or a protein based vaccine, where to find PEMGARDA, and information for Columbia Unversity Irving Medical Center’s long COVID treatment center.

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  • Is the mysterious disease in the Congo, malaria? (AP News) 5:05
  • State of global health, year-end remarks by WHO director-general (WHO)
  • Really, progress towards poliomyelitis eradication? (CDC MMWR) 7:47
  • Increases in confirm cases ¹ control of poliomyelitis (WHO) 9:10
  • Polio European Union and United Kingdom, is that 1 global entry? (Science) 10:41
  • Is the WHO the global CDC?  polio vaccination guidelines (WHO) 14:41
  • Do you feed your cats raw milk? (Public Health LA county) 16:39
  • Is there avian influenza in the zoo near you? (Maricopa) 17:32
  • Don’t feed your cat raw milk (CIDRAP)
  • Holy Cow! H5N1 in cows! (microbeTV) 18:20
  • Tecovirimat no improvement in Mpox resolution or pain (NIAID NIH) 18:52
  • Interim results from STOMP study of  Tecovirimat (SIGA) 19:18
  • Trial stops enrollment after Tpoxx fails (CIDRAP) 1918
  • Is Tecovirimat really first-in-class mpox therapy? (Viruses)
  • Influenza weekly surveillance report: clift notes (CDC FluView) 21:03
  • US respiratory virus activity (CDC Respiratory Illnesses) 21:03
  • Waste water scan for 11 pathogens (WastewaterSCan) 21;56
  • RSV-Network (CDC Respiratory Syncytial virus Infection) 22:25
  • COVID-19 deaths (CDC)
  • COVID-19 national and regional trends (CDC) 23:20
  • Waste water scan for 11 pathogens (WastewaterSCan) 23:28
  • COVID-19 variant tracker (CDC)
  • SARS-CoV-2 genomes galore (Nextstrain)
  • Relative effectiveness of homologous NVX-CoV2373 and BNT162b2 COVID-19 vaccinations in South Korea (Vaccine) 24:46
  • Phase III trial results! Comparative efficacy and safety of COVID-19 (BMC Infectious Diseases) 26:23
  • Where to get pemgarda (Pemgarda)
  • EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
  • Fusion center near you….if in NY (Prime Fusions)
  • CDC Quarantine guidelines (CDC)
  • NIH COVID-19 treatment guidelines (NIH)
  • Infectious Disease Society guidelines for treatment and management (ID Society)
  • Drug interaction checker (University of Liverpool)
  • Molnupiravir safety and efficacy (JMV)
  • Convalescent plasma recommendation for immunocompromised (ID Society)
  • What to do when sick with a respiratory virus (CDC)
  • When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
  • Managing healthcare staffing shortages (CDC)
  • Stop playing favorites with COVID-19 in healthcare settings (Infection Control & Hospital Epidemiology) 27:51
  • Steroids, dexamethasone at the right time (OFID)
  • Anticoagulation guidelines (hematology.org)
  • Remdesivir Effectiveness in Reducing the Risk of 30-day Readmission in Vulnerable Patients Hospitalized for COVID-19 (CID)
  • Daniel Griffin’s evidence based medical practices for long COVID (OFID)
  • Long COVID hotline (Columbia : Columbia University Irving Medical Center)
  • Letters read on TWiV 1174 35:13
  • Dr. Griffin’s COVID treatment summary (pdf)
  • Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV reviews nominees to head NIH, FDA, and CDC, cervical cancer decline following HPV vaccination, local dengue in Texas, human isolate of H5N1 virus is transmissible and virulent in animal models, and shared mechanisms of immune evasion among animal and bacterial viruses.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey

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Weekly Picks 1:32:28

BriannePale Blue Pod
KathyPhysicsGirl recent Instagram post, ScienceAdvisor signup free daily sci news distillation, Semi-conducting hydrogels, Bot that can pick up things with a soft touch, “Pigeonbot II”, a drone called LisRaptor, zapping forever chemicals like PFAS with light and here
RichVendee Globe
JoleneCenter for the Improvement of Mentored Research Experiences
VincentThese two ancient human relatives crossed paths 1.5 million years ago

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.