From the 2024 International Hepatitis B virus meeting in Chicago IL, Rich Condit speaks with Stephan Urban about his career working on HBV and HDV, and his philanthropy.

Host: Rich Condit

Guest: Stephan Urban

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Intro music is by Ronald Jenkees

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TWiV discusses the rising autism rate among children, RFK Jr.’s claim that autism ‘destroys lives’, receptor binding specificity of a bovine H5N1 influenza virus, and improved dengue subunit vaccine modified to form E protein dimers.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker

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Weekly Picks 1:19:46

BrianneScientists detect signature of life on a distant planet, study suggests
RichHanlon’s Razor
Alan – Baby colossal squid filmed in deep ocean
Vincent How the United States became a science superpower — and how quickly it could crumble

Listener Pick

JohnRevisionist History: The RFK Jr. Problem

Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello rue about the continuation of the gutting of the American public health infrastructure, the continuing measles outbreak, an unreported outbreak of deadly E.coli human infections, meningococcal disease before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, ACIP recommended changes in guidelines for the RSV and COVID-19 vaccines, reactogenicity differences between Novavax and Pfizer COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, effects of long COVID in children and adolescents and a list of ongoing clinical trials for long COVID treatment.

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Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

TWiV reviews RFK Jr’s odd comments on ‘single antigen’ vaccines and his September deadline for understanding why autism has increased, dire wolf does not come back from the dead, oral norovirus vaccine tablet that induces mucosal immunity in older adults, and identification of broadly neutralizing human monoclonal antibodies against norovirus.

Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker

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Weekly Picks 1:28:14

BrianneNew experiment updates classic experiment on how life on Earth started
KathyAPOD ISS meets Venus, Sign up for NASA ISS alerts, GoISS Watch
Alan – Mason bees could replace honeybees as crop pollinators
VincentMystery of medieval manuscripts revealed by ancient DNA

Listener Pick

SonrisaGOT’EM Good!

Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello mourn the demise of vaccination against childhood diseases when discussing the continuing measles outbreak and the rise of pertussis, the first human case of H5N1 in Mexico, and human metapneumovirus before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, if antiviral therapy prevents long COVID and how long COVID may affect brain volume.

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Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

TWiV notes the passing of Klaus Conzelmann, then reviews reverse-zoonoses of 2009 H1N1 pandemic influenza A viruses and evolution in United States swine, and reduction in dementia incidence in recipients of Zostavax.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

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Weekly Picks 1:34:00

RichCertain Roller Coasters May Help Small Kidney Stones Pass
AlanAnalog and Asimov’s science fiction magazines
VincentScience Under Threat in the United States: How scientists and institutions should respond

Listener Pick

CharlesWhy Techdirt Is Now A Democracy Blog (Whether We Like It Or Not)

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello lament about the continuing measles outbreak, whether or not the measles outbreak was predicted, the FACTS about vaccination, high pathogenic influenza, H5N1 contaminated raw pet food, children’s deaths, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules and the efficacy of Moderna’s seasonal mRNA vaccine, societal burden of COVID-19 and influenza, the FDA missed deadline for approving Novovax COVID vaccine, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, and Canada’s long COVID dashboard.

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  • CDC buried a measles forecast that stressed the need for vaccinations….TRANSPARENCY? (Politico) 5:16
  • Measles cases and outbreaks (CDC Rubeola) 7:11
  • Measles 159 in Texas…. (Texas Health and Human Services) 10:28
  • 2025 Measles outbreak guidance (New Mexico Health) 10:45
  • Measles and rubella weekly monitoring report (Government of Canada) 11:20
  • Enhanced epidemiological summary Measles in Ontario (Public Health Ontario) 11:01
  • Measles and rubella weekly monitoring report (Government of Canada)
  • Enhanced epidemiological summary Measles in Ontario (Public Health Ontario)
  • Measles exposures in Ontario (Public Health Ontario)
  • Measles vaccine recommendations from NYP (jpg) 11:46
  • Get the FACTS about measles (NY State Department of Health)
  • Measles (CDC Measles (Rubeola))
  • Measles vaccine (CDC Measles (Rubeola))
  • Presumptive evidence of measles immunity (CDC)
  • Contraindications and precautions to measles vaccination (CDC)
  • Measles (CDC Measles (Rubeola))
  • Raw cat food tests positive for H5N1 (CIDRAP) 12:24
  • Influenza: Waste water scan for 11 pathogens WastewaterSCan) 13:20
  • US respiratory virus activity (CDC Respiratory Illnesses) 13:48
  • Weekly surveillance report: clift notes (CDC FluView)
  • Respiratory virus activity levels (CDC Respiratory Illnesses)
  • FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA) 14:00
  • RSV: Waste water scan for 11 pathogens (WastewaterSCan) 14:10
  • US respiratory virus activity (CDC Respiratory Illnesses) 14:10
  • RSV-Network (CDC Respiratory Syncytial virus Infection)
  • Early impact of RSV vaccination in older adults in England (Lancet) 14:25
  • Waste water scan for 11 pathogens (WastewaterSCan) 16:28
  • COVID-19 deaths (CDC) 16:42
  • COVID-19 national and regional trends (CDC) 16:42
  • COVID-19 variant tracker (CDC)
  • SARS-CoV-2 genomes galore (Nextstrain)
  • Evaluating the effectiveness of 2024-2025 seasonal mRNA-1273 vaccination against covid-19-associated hospitalizations and medically attended covid-19 among adults aged ≥ 18 years in the united states (medRxiv) 18:48
  • Current Moderna vaccine 53% effective against COVID hospitalization? (CIDRAP)
  • Preliminary estimates of COVID-19 burden for 2024-2025 (CDC COVID-19) 24:08
  • Estimated range of annual burden of flu in the US from 2010 – 2024 (CDC-flu burden) 24:01
  • US FDA missed the deadline for decision on Novavax’s COVID-19 vaccine (Reuters) 25:40
  • Interim clinical considerations for use of COVID-19 vaccines in the United States (CDC Vaccines & Immunizations) 27:05
  • Where to get pemgarda (Pemgarda)
  • EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
  • Fusion center (Prime Fusions)
  • CDC Quarantine guidelines (CDC)
  • NIH COVID-19 treatment guidelines (NIH)
  • Metformin alleviates inflammatory response and severity rate of COVID-19 infection in elderly individuals (Scientific Reports) 27:59
  • Drug interaction checker (University of Liverpool)
  • Infectious Disease Society guidelines for treatment and management (ID Society)
  • Cost-effectiveness analysis of nirmatrelvir/ritonavir for high-risk individuals with COVID-19….does this mean use the big button calculator? (OFID) 35:55
  • Molnupiravir safety and efficacy (JMV)
  • Convalescent plasma recommendation for immunocompromised (ID Society)
  • What to do when sick with a respiratory virus (CDC)
  • When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC
  • Managing healthcare staffing shortages (CDC)
  • Steroids, dexamethasone at the right time (OFID)
  • Anticoagulation guidelines (hematology.org)
  • Daniel Griffin’s evidence based medical practices for long COVID (OFID)
  • Long COVID hotline (Columbia : Columbia University Irving Medical Center)
  • The answers: Long COVID
  • Reinfection with SARS-CoV-2 in the omicron era is associated with increased risk of post-acute sequelae of SARS-CoV-2  infection: a recover-EHR cohort study (medRxiv) 37:24
  • CAN-PCC RecMap, your one-stop shop for recommendations about Post COVID-19 Condition (Long COVID) (Canadian Guidelines for post COVID-19 condition) 41:25
  • Letters read on TWiV 1206 43:58
  • Dr. Griffin’s COVID treatment summary (pdf)
  • Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews liver damage caused by over use of vitamin A in Texas, vitamin A does not change clinical course of measles in high income country, NIH cuts COVID-19 research, US ends vaccine funds for poor countries, anti-vaxxer hired to study vaccines and autism, new DURC policy, Jamaican fruit bat competence for filoviruses, and human outbreaks of Oropouche virus reassortant in Brazil.

Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker

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Weekly Picks 1:32:12

BrianneMath of March Madness Brackets
Kathy – Wood frogsicles #1 and #2
Alan – Rare glimpse of baby polar bears emerging from dens
VincentHikaru Utada Would Rather Play CERN Than Coachella

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello rue about the continuing measles outbreak, the FACTS about vaccination, irresponsibility of promoting vitamin A therapy “lifelong liver damage or vaccinaton!”, high pathogenic influenza and egg importation before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules and if vaccination affects long COVID, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, how to track long symptoms using a wearable device and how these data will never be used with the closing of governmental long COVID programs and offices.

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Download TWiV 1204 (31 MB .mp3, 51 min)
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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains why RFK Jr.’s proposal to let H5N1 infections in birds ‘rip’ is a bad idea, phase 1/2 trial of combined influenza/COVID mRNA vaccines, and how your first influenza virus exposure shapes the B cell response to influenza vaccination 50 years later.

Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker

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Weekly Picks 1:38:52

BrianneNode-Focal Plane Image Competition
RichPeriodic cooking of eggs
VincentThe use of placebo controls in clinical trials

Listener Picks

AnneEverything is Tuberculosis by John Green

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.