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Tag: spleen

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TWiP 180: A spleen palaver

  • February 8, 2020
  • Tagged as: artemisinin, clathrin, endocytosis, hemoglobin, kelch13, malaria, parasite, parasite food vacuole, parasitism, parasitology, Plasmodium, spleen, splenomegaly, Uganda

The TWiP professors solve the case of the Ugandan Child with Splenomegaly, and reveal that mutations in the P. falciparum genome that confer artemisinin resistance interfere with endocytic uptake of hemoglobin.

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Christina Naula, Ph.D.


Daniel Griffin, M.D.,

Vincent Racaniello, Ph.D.


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