TWiP explains a study that carries out selection of Plasmodium falciparum in the presence of inhibitors to identify determinants of drug resistance, and a paleoparasitological analysis of a 5th–16th c. CE latrine. Hosts: Vincent Racaniello, Daniel…
TWiP discusses a study of the safety and immunogenicity of a late liver-stage attenuated malaria parasite delivered by mosquito bite. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Click arrow to playDownload TWiP #252 (78 MB…
TWiP 240: A daily history of malaria with Sean Murphy
- August 2, 2024
- Tagged as: dried blood spot, malaria, parasite, parasitism, parasitology, Plasmodium, ribosomal RNA, RT-PCR, Uganda
Sean Murphy joins TWiP to discuss his career and the work of his laboratory to assess the daily natural history of asymptomatic Plasmodium infections in adults and older children in Katakwi, Uganda.
Marion Avril of MalarVx, Inc. joins TWiP to discuss an accelerated prime-and-trap regimen using repRNA-based circumsporozoite vaccine.
TWiP 228: Parasitic fountain of youth
- February 6, 2024
- Tagged as: ant worker, malaria, monoclonal antibody, parasite, parasitism, parasitology, tapeworm, vaccine
TWiP discusses a tapeworm that causes extreme lifespan extension in infected ant workers, and a candidate antibody drug for prevention of malaria.
TWiP 226: Successful systems attract parasites
- January 3, 2024
- Tagged as: childhood stunting, climate change, malaria, parasite, parasitism, parasitology
TWiP reviews some parasite stories of 2023, including progress in the control of malaria and polio, and review a connection between parasites and childhood stunting.
TWiP 224: Neglected tropical diseases roadmap with Chuck Knirsch
- December 12, 2023
- Tagged as: malaria, neglected tropical diseases, NTD roadmap, parasite, parasitism, parasitology, trachoma, WHO
Chuck Knirsch returns to TWiP to discuss the Neglected Tropical Diseases Roadmap published by WHO, which sets global targets and milestones to prevent, control, eliminate or eradicate 20 diseases and disease groups.
TWiP 223: Voluminous diarrhea
- November 28, 2023
- Tagged as: diarrhea, malaria, parasite, parasitism, parasitology, vaccine
TWiP solves the case of the Haitian female with AIDS and voluminous diarrhea, and review the pathogenesis, epidemiology, prevention and treatment of malaria Chagas disease.
TWiP 220: Denies any bug bites
- August 20, 2023
- Tagged as: babesia, malaria, mRNA vaccine, parasite, parasitism, parasitology, T cell, tick, vaccine
TWiP solves the case of the Hiker from Queens who Denies Bug Bites, and reveal two different malaria experimental vaccines that target different parts of the parasite life cycle.
TWiP solves the case of the 19 month old Female Having Issues, and discusses the finding that selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles mosquitoes.
