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Category: Episodes

  • Episodes

TWiP 178: The shadowlands of medicine

  • December 4, 2019
  • Tagged as: antimalaria drug, Chilomastix mesnili, Dientamoeba fragilis, gastroenteritis, malaria, ova and parasites, parasite parasitism, parasitology, Plasmodium falciparum, protein kinase

The Knights of the TWiP solve the case of the Man Who Lost Weight, and discuss a Plasmodium protein kinase that is a malarial drug target.

1 Reply
  • Episodes

TWiP 177: A scabrous education

  • November 6, 2019
  • Tagged as: cercariae, mite, parasite, parasitism, parasitology, permethrin, rotifer, sarcoptes Scabiei, scabies, schistosomiasis, snail intermediate host

The TWiPsters solve the case of the Rashy Schoolteacher, and reveal a drug from rotifers that live on the snail intermediate host which paralyzes schistosome cercariae and prevents infection of mice.

1 Reply
  • Episodes

TWiP 176: Blood schmear

  • October 9, 2019
  • Tagged as: AIDS, babesia, babesiosis, blood smear, CD4+ lymphocyte, HIV-1, Maltese cross, parasite, parasitism, parasitology, schistosome, soluble egg antigen, tick

The TWiPpers of the bite fantastic solve the case of the Indian Man Who Hiked, and discuss the effects of schistosome soluble egg antigen on infection of lymphocytes with HIV-1.

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  • Episodes

TWiP 175: None alone pathognomonic

  • September 4, 2019
  • Tagged as: erythrocyte invasion, Kala Azar, Leishmania donovani, leishmaniasis, malaria, malaria vaccine, neutralizing antibodies, non-neutralizing antibodies, parasite, parasitism, parasitology, PfRH5, sandfly, Sudan

The TWiP’ers solve the case of the Sudanese Boy With Fever, and reveal antibodies that slow invasion of red blood cells potentiate other malaria-blocking antibodies

1 Reply
  • Episodes

TWiP 174: Fat cat

  • August 1, 2019
  • Tagged as: cat, definitive host, delta-6-saturase, feline, Linoleic acid, parasite, parasitism, parasitology, sexual stages, toxoplasma gondii

The TWiPloid organisms solve the case of the Doctor with Chronic Epigastric Pain, and reveal how levels of linoleic acid in the intestine enable the sexual cycle of Toxoplasma gondii in cats.

1 Reply
  • Episodes

TWiP 173: Rose colored spots

  • July 13, 2019
  • Tagged as: clinical case, dysentery, Entamoeba histolytica, narnavirus, parasite, parasitism, parasitology, Plasmodium, rose spots, Salmonella

The podcastellani hosts solve the case of the Sailor With Dysentery, and reveal the first virus discovered in Plasmodium species.

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  • Episodes

TWiP 172: A painless lesion

  • June 14, 2019
  • Tagged as: cutaneous leishmaniasis, malaria, Metarhizium, mosquito, painless lesion, parasite, parasitism, parasitology, sandfly, spider venom, transgenic, transgenic fungus

The metacyclic TWiPomastigotes solve the case of the Child With a Painless Leg Lesion, and reveal how to kill mosquitoes with a genetically modified fungus.

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  • Episodes

TWiP 171: Better than a sharp stick in the eye

  • May 23, 2019
  • Tagged as: Amoebophyra, band keratopathy, dinoflagellate, eukaryotic parasite, harmful algal bloom, mitochondrial genome, mitochondrion, parasite, parasitism, parasitology, toxoplasma gondii

The Leishmaniacs solve the case of the Child With Band Keratopathy, and reveal a eukaryotic parasite with functional mitochondria but without mitochondrial genomes.

1 Reply
  • Episodes

TWiP 170: A worm’s eye view

  • May 8, 2019
  • Tagged as: Chagas disease, collection-11, complement protein, MASP2, parasite, parasitism, parasitology, retinal granuloma, Toxocara canis, Toxocara cati, Trypanosoma cruzi

The TWiPlicates solve the case of the Child With Retinal Granuloma, and discuss an association of the complement protein collectin-11 with the pathophysiology of Chagas disease.

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  • Episodes

TWiP 169: What goes on in the snail

  • April 10, 2019
  • Tagged as: Ascaris lumbricoides, hybrids, intestinal worm, parasite, parasitism, parasitology, recombination, Schistosoma bovis, Schistosoma haematobium

The TriTWiPomonads solve the case of the Child Who Passed a Worm, and reveal recombination between bovine and human schistosome species.

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