TWiN explains how central nervous system resident macrophages known as microglia coordinate cellular interactions during spinal cord repair in mice.
TWiN describes how neurotropic viruses leave the brain via meningeal lymphatic vessels located dorsally and basally beneath the skull.
TWiN 32: Relearning how to move after stroke
- August 2, 2022
- Tagged as: cortex, neurobiology, neuroscience, recovery after stroke, striatum, stroke
TWiN reviews how, in a mouse stroke model, recovery of movement is associated with the remaining cortex and the striatum coordinating their activity together.
TWiN 31: HIV-1 co-receptor shapes window for memory linking
- June 29, 2022
- Tagged as: CCR5, maraviroc, memory, memory linking, neurobiology, neuron, neuroscience
TWiN explains the observation that in mice, the HIV-1 co-receptor CCR5 closes the temporal window for linking different memories.
TWiN describes experiments demonstrating that gut injection of alpha-synuclein fibrils in mice converts endogenous alpha-synuclein to a pathologic form that spreads to the brain and leads to features of Parkinson’s disease.
TWiN explains the finding that in the mouse visual cortex, astrocytes are key elements in the experience-dependent wiring of brain circuits.
TWiN reveals how oligodendrocytes enhance axonal energy metabolism by transcellular delivery of a protein, SIRT2, that deacetylates mitochondrial proteins.
TWiN discusses the finding that rewiring retinal projections to the auditory thalamus in ferrets leads to visually responsive cells that are typical of cells in the visual cortex.
TWiN 26: Immunological memory in the brain
- January 26, 2022
- Tagged as: brain, immune respose, memory, neurobiology, neuroscience
TWiN reviews evidence in mice that brain neurons encode and retrieve specific immune responses.
TWiN 25: Thanks for listening
- December 28, 2021
- Tagged as: memory, neurology, neuron, neuroscience, odorant receptor, sex
TWiN answers listener questions on sex in neuroscience studies, rotating memories in the brain, odorant receptors in the brain, and neutrophils that promote neuron survival.