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Tag: neuroscience

  • This Week in Neuroscience

TWiN 12: A gene for short-term memory

  • November 11, 2020
  • Tagged as: brain, collaborative cross mice, diversity outbred mice, nerve, neurology, neuroscience, orphan receptor, short term memory, spinal cord, thalamus, working memory

Ori, Jason, and Vincent reveal identification of an orphan receptor that modifies short-term memory in mice, and a mouse model of COVID-19 that includes anosmia or loss of smell.

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  • This Week in Neuroscience

TWiN 11: A dollar per neuron

  • October 14, 2020
  • Tagged as: astrocyte, brain cortex, evolution, interneuron, mammals, neuron, neuroscience, reptiles, single cell transcriptomics

Maria joins TWiN to explain how single-cell transcriptomics is being used to reveal the evolution of the brain, at a cost of about $1 per neuron.

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  • This Week in Neuroscience

TWiN 10: Remodeling synapses with a cytokine

  • September 29, 2020
  • Tagged as: cytokine, hippocampus, IL-33, microglia, neurology, neuron, neuronal circuit, neuroscience, spine plasticity, synapse remodeling

TWiN explains how a cytokine produced by neurons activates microglia which modify the extracellular matrix and remodel synapses, leading to memory consolidation.

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  • This Week in Neuroscience

TWiN 9: COVID-19 neurology with Genna Waldman

  • August 11, 2020
  • Tagged as: cognitive defect, coma, COVID-19, hypoxia, neurobiology, neuroinvasion, neurological symptoms, neurology, neuropathology, neuroscience, pandemic, SARS-CoV-2, stroke, thrombosis

Columbia University Chief Neurology Resident Genna Waldman joins TWiN to explains how her department prepared for COVID-19, and the neurological symptoms associated with the disease.

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  • This Week in Neuroscience

TWiN 8: Replacing lost neurons

  • July 7, 2020
  • Tagged as: astrocytes, CRISPR, dopamine, gene editing, glial cells, neurology, neurons, neuroscience, neurotransmitter

TWiN explains how neurological disease in mice can be repaired by using CRISPR/Cas to knock down levels of a single cell protein, which converts astrocytes to neurons.

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  • This Week in Neuroscience

TWiN 7: Stress, the good, bad and beautiful

  • June 13, 2020
  • Tagged as: antibodies, B cells, brain, germinal center, gray hair, immune responses, nerves, nervous system, neuroscience, spinal cord, spleen, stress, T cells

The TWiN team reveals how the nervous system controls hair graying in mice subjected to stress, and adaptive immune responses.

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  • This Week in Neuroscience

TWiN 6: Neural control of sexual behavior

  • May 20, 2020
  • Tagged as: brain, gender, neurobiology, neuroscience, sexual behavior

Nirao Shah joins TWiN to discuss the work of his laboratory on how our brains generate social interactions that differ between the sexes.

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  • This Week in Neuroscience

TWiN 5: Anosmia and COVID-19

  • April 18, 2020
  • Tagged as: anosmia, COVID-19, loss of smell, nasal olfactory epithelium, nervous system, neurobiology, neuroscience, SARS-CoV-2

Bob Datta joins TWiN to reveal the findings of his laboratory on expression of SARS-CoV-2 entry genes in the olfactory epithelium and the implications for anosmia associated with COVID-19.

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  • This Week in Neuroscience

TWiN 4: It’s a trap!

  • January 9, 2020
  • Tagged as: ACBAR, exoxomes, gag protein, information transfer, memory, neurology, neuroscience, retrotransposon, synapse

Jason visits the TWiN studio to explain Arc Capsid Bearing Any RNAs (ACBARs), virus-like capsids that transfer genetic information between neurons.

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  • This Week in Neuroscience

TWiN 3: Gambling on dopamine

  • December 18, 2019
  • Tagged as: addiction, dopamine, dopamine neurons, gambling, nervous system, neuron, neuroscience, Pavlovian procedure, reward probability, risky behavior, uncertainty

Erin and the TWiN team explain how dopamine neurons encode reward probability and uncertainty, and their roles in attention-based learning and risk-taking such as gambling and addiction.

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