TWiM explains unique modifications in the energy conservation pathways linked to methanogenesis in an Archaeon, and mechanisms of white nose fungal invasion of cells from the Little Brown Bat.
TWiM explains how spindle-shaped Archaeal viruses evolved from rod-shaped ancestors to package a larger genome, and transcriptional recording by CRISPR acquisition from RNA.
TWiM reveals that methane-producing bacteria might survive beneath the surface of Mars, and identification of a cytopathogenic toxin in a bacterium associated with preterm birth.
Sam Sternberg discusses his work on exploring and exploiting CRISPR-Cas immune systems, beginning as a graduate student with Jennifer Doudna, at a biotech start-up, and in his laboratory at Columbia University.
Vincent, Michael and Elio note the passing of Stanley Falkow, give E. coli an archaeal membrane, and show how the microbiome can make worms live longer.
The TWiM team provides an update on Zika virus, and reveals a plasmid on the road to becoming a virus.
Vincent, Elio, and Michael reveal what Neanderthals ate from analysis of DNA in their teeth, and new CRISPR-Cas systems found in the genomes of uncultured microbes.
Vincent, Michael, and Stanley review the scientific career of Carl Woese.
The Hosts of TWiM
Petra Levin, Ph.D.
Michele Swanson, Ph.D.
Michael G. Schmidt, Ph.D.
Vincent Racaniello, Ph.D.