TWiEVO 86: Pulling out the stops in genetic code evolution

February 2, 2023

Nels and Vincent discuss how evolution of changes in stop codon assignment might occur, and a novel mechanism for altering the meaning of translation stop codons discovered in a trypanosomatid with the apropos name, Blastocrithidia nonstop.

Hosts: Nels Elde and Vincent Racaniello

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Download TWiEVO 86  (55 MB .mp3, 97 min)
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•Join the MicrobeTV Discord server 1:41:59
•Novel stop codon reassignment mechanisms (Nature) 9:15

Science Picks 1:31:02

NelsProtein Synthesis: An epic on the cellular level 

VincentWidespread stop-codon recoding in bacteriophages may regulate translation of lytic genes discussed on TWiM 277

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