Nels and Vincent explain a method to calculate the mutation rate of SARS-CoV-2, and the role of a single amino acid change in spike in enhancing fitness of the delta variant and enabling it to out-compete the alpha variant.
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Links for this episode
- SARS-CoV-2 mutation rate (Genome Biology Evolution) 7:10
- Delta spike change enhances fitness (bioRxiv) 48:17
- Time stamps by Jolene. Thanks!
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Thomas – The gene’s-eye view of evolution by J. Arvid Ågren
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