Nels and Vincent continue their discussion of SARS-CoV-2 from an evolutionary viewpoint, focusing on what the genome sequences tell us about the virus.
Hosts: Nels Elde and Vincent Racaniello
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Download TWiEVO 53 (56 MB .mp3, 92 min)
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- Clement Chow with COVID-19 (Salt Lake Trib) 11:30
- Scientists exposed to coronavirus (Nature) 14:15
- CoV by Britt Glaunsinger (YouTube) 25:50
- Genetic epidemiology of novel coronavirus (nextstrain.org) 31:01, 42:21
- Time stamps by Jolene. Thanks!
Science Picks 1:24:55
Nels – Science Mill Explorer Zone
Vincent – COVID-19 treatment and therapy tracker
Music on TWiEVO is performed by Trampled by Turtles
Send your evolution questions and comments to twievo@microbe.tv
Hi Vincent and Nels,
thanks for your great podcast.
I have a question regarding your estimates of coronavirus mutation rate. You sort of downgraded that on the podcast (rightfully so, considering how media react to those). but while the nextstrain.org gives an 24.75 subs/year for ncov, it also contains dataset for other viruses. So for flu they have 3.53e-3/site/year, which matches well with the literature I think. However, when comparing apples to apples it is 8e-4 for ncov, or roughly 4 times less the mutation rate of the influenza virus.
While this is definitely smaller, but still pretty much comparable, don’t you think?
thanks again for your great podcast, it’s an essential part of my ‘shelter in place’ routine these days,
Victor,
Moscow, Russia
a student of Vincent online courses since 2014
What a pleasant conversation about the science of CoV-2 and beyond. The measured and knowledgeable voice of Dr. Elde through the welcome nudges of Vincent provides a welcome window into our current context and future challenge opportunities.
Thank you for this conversation that welcomes laypersons into it. You both are so well-spoken. Impressive!
Thank you, Nels, for your depth of knowledge, experience, and research in this important SCIENCE!
RT
noob here, divergence number in nextstrain means?
i.e.: “Divergence: 7.962”
When tree is changed from time to divergence it gets higher from left to right.
Could it be possible to have a transcript for those who can’t hear please?
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