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Tag: natural selection

  • Episode

TWiEVO 46: Can an old tumor teach us new tricks?

  • August 31, 2019
  • Tagged as: APOBEC, cancer lineage, canine transmissible tumor, evolution, mutational signature, natural selection, somatic evolution

Nels and Vincent analyze the genomes of canine transmissible tumors to provide insight into the worldwide spread of the disease from its origin in a single dog 4000-8500 years ago, and its diversity, mutation, and evolution.

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  • Episode

TWiEVO 42: Who’s who in your genome

  • April 24, 2019
  • Tagged as: adaptation, archaic human, Denisovan, evolution, genome sequences, hominid, introgression, natural selection, Papuans

Nels and Vincent review the contribution of multiple Denisovan lineages to the modern Papuan genome.

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  • Episode

TWiEVO 41: Where do baby genes come from?

  • March 20, 2019
  • Tagged as: adaptive evolution, antifreeze protein, de novo gene, evolution, natural selection, nogenic, noncoding gene, noncoding origin, northern codfish, proto-ORF

Nels and Vincent explore the evolution of new protein-coding genes de novo from nocoding DNA sequences, using the antifreeze protein of northern codfish as a model.

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  • Episode

TWiEVO 40: Eau de bee

  • February 15, 2019
  • Tagged as: courtship display, evolution, natural selection, odorant receptor, olfactory receptor, orchid bee, reproductive isolation, speciation, species identity

Nels and Vincent move back to reproductive isolation – this time, pre-zygotic, in the charismatic orchid bee where the males make chemically distinct perfumes to attract mates of the same species.

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  • Episode

TWiEVO 34: You don’t know what you’ve got ‘til it’s PON

  • August 16, 2018
  • Tagged as: agricultural runoff, cetacean, evolution, gene loss, marine mammal, natural selection, organophosphorus, paraoxonase, pesticide, pinniped, sirenian

Nels and Vincent discuss how the loss of an enzyme in marine mammals millions of years ago now makes them at risk for neurotoxicity caused by human-made organophosphorous pesticides.

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  • Episode

TWiEVO 32: Never not neutral

  • June 19, 2018
  • Tagged as: adaptation, evolution, mutation, natural selection, neutral theory of evolution, population genetics, spandrel, TWiEVO

Matt joins Nels and Vincent to discuss the neutral theory of evolution and its rejection in light of genome-scale data.

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  • Episode

TWiEVO 30: Driving Miss Maize-y

  • April 21, 2018
  • Tagged as: chromosome segregation, corn, evolution, Kindr, kinesin, maize, natural selection, neocentromere, non-Mendelian inheritance

Nels and Vincent reveal how a motor protein in corn causes preferential transmission of chromosomes to egg cells, leading to non-Mendelian inheritance

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  • Episode

TWiEVO 29: Evolution on the wing

  • March 21, 2018
  • Tagged as: blood feeding, blood meal, evolution, evolution of virulence, house finch, incomplete immunity, mosquito, mycoplasma, natural selection, nonbiting mosquito, transcriptome

Nels and Vincent discuss the evolution of blood feeding to nonbiting in a mosquito, and evolution of bacterial virulence in the house finch caused by incomplete host immunity.

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  • Episode

TWiEVO 25: Pigeons show the way

  • November 22, 2017
  • Tagged as: drift, evolution, extinction, genome, mitochondrial genome, mutation, natural selection, passenger pigeon, population

Nels and Vincent discuss a genomic analysis of the passenger pigeon, which shows that species with large and stable populations may be at risk of extinction after a sudden environmental change.

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  • Episode

TWiEVO 20: In the company of cnidarians

  • June 19, 2017
  • Tagged as: cnidarian, coral, dinoflagellate, evolution, natural selection, sea anemone, symbiosis, thrombospondin type 1 protein repeat, TSR protein
TWiEVO

Nels and Vincent explore the role of TSR proteins during colonization of cnidarians by dinoflagellates.

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The Hosts of TWiEVO

Nels Elde, Ph.D.


Vincent Racaniello, Ph.D.


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