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Tag: APOBEC

  • Episode

TWiEVO 46: Can an old tumor teach us new tricks?

  • August 31, 2019
  • Tagged as: APOBEC, cancer lineage, canine transmissible tumor, evolution, mutational signature, natural selection, somatic evolution

Nels and Vincent analyze the genomes of canine transmissible tumors to provide insight into the worldwide spread of the disease from its origin in a single dog 4000-8500 years ago, and its diversity, mutation, and evolution.

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  • Episode

TWiEVO 2: Faster than a speeding virus

  • December 26, 2015
  • Tagged as: APOBEC, enzyme, evolution, HIV, human immunodeficiency virus, mutation, mutation rate, viral, virology, virus, viruses
TWiEVO

Nels and Vincent talk about how a cellular enzyme contributes to the very high mutation rate of human immunodeficiency virus type 1.

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