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Tag: mutation

  • Episode

TWiEVO 57: SARS-CoV-2 receptor binding evolution blooms

  • June 24, 2020
  • Tagged as: deep mutational scanning, evolution, mutation, natural selection, receptor binding domain, SARS-CoV-2

Jessie, Allie and Tyler join Nels and Vincent to describe their work on deep mutational scanning of the SARS-CoV-2 receptor binding domain.

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  • Episode

TWiEVO 32: Never not neutral

  • June 19, 2018
  • Tagged as: adaptation, evolution, mutation, natural selection, neutral theory of evolution, population genetics, spandrel, TWiEVO

Matt joins Nels and Vincent to discuss the neutral theory of evolution and its rejection in light of genome-scale data.

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  • Episode

TWiEVO 25: Pigeons show the way

  • November 22, 2017
  • Tagged as: drift, evolution, extinction, genome, mitochondrial genome, mutation, natural selection, passenger pigeon, population

Nels and Vincent discuss a genomic analysis of the passenger pigeon, which shows that species with large and stable populations may be at risk of extinction after a sudden environmental change.

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  • Episode

TWiEVO 2: Faster than a speeding virus

  • December 26, 2015
  • Tagged as: APOBEC, enzyme, evolution, HIV, human immunodeficiency virus, mutation, mutation rate, viral, virology, virus, viruses
TWiEVO

Nels and Vincent talk about how a cellular enzyme contributes to the very high mutation rate of human immunodeficiency virus type 1.

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The Hosts of TWiEVO

Nels Elde, Ph.D.


Vincent Racaniello, Ph.D.


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