TWiV 1200: Clinical update with Dr. Daniel Griffin

March 15, 2025

In his weekly clinical update, Dr. Griffin and Vincent Racaniello bemoan the continued outbreak of Sudan virus and growing number of paralytic polio cases before discussing growing measles outbreak in the US and Europe, the vaccine, an interview with a parent whose child died of measles infection, adverse effects of vaccination and how parents do not think they have accurate information about “bird flu” before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, what happens when antiviral therapy is delayed, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions and the benefits of antiviral therapies on post acute SARS-Cov-2 infection sequelae.

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  • Sudan virus disease (WHO) 3:00
  • New cases of poliomyelitis  (GPEI) 5:08
  • Measles 159 in Texas (Texas Health and Human Services) 8:01
  • 2025 Measles outbreak guidance (New Mexico Health) 8:15
  • First cases of measles in Oklahoma (Oklahoma) 8:40
  • Measles case on Long Island (CBS News) 8:48
  • Public health confirms measles case in Los Angeles County (County of LA Public Health) 9:31
  • Measles exposure (Department of public health: City of Philadelphia) 9:46
  • Where US measles outbreaks are spreading (New York Times) 9:56
  • Statement from the chief public health officer of Canada on the increase in measles cases and the risk to people in Canada(Health Canada) 11:30
  • Measles and rubella monthly report (ecdc) 15:32
  • Measles on the rise again in Europe (EurekAlert) 15:32
  • Measles: symptoms, spread & SSPE Children’s Hospital of Philadelphia (YouTube) 17:15
  • Measles (CDC Measles (Rubeola)) 7:45
  • Adverse events associated with childhood vaccines: evidence bearing on causality (NLM: NCBI)
  • Measles vaccination: know the facts? (Infectious Diseases Society of America)
  • Deaths following vaccination: What does the evidence show? (Vaccine) 22:38
  • Facts and myths about measles (LANCET: Infectious Diseases) 18:58, 23:45
  • His daughter was America’s first measles death in a decade (The Atlantic) 26:31
  • Less than half of parents think they have accurate information about bird flu (EurekAlert) 27:20
  • Many US parents feel uninformed about avian flu risks (CIDRAP)
  • Trends in respiratory pathogen testing at us children’s hospital (JAMA Network) 32:49
  • Changes in respiratory viral testing before and after the covid-19 pandemic (JAMA Network) 32:53
  • Free COVID-19 test program stops taking orders (Health day) 38:11
  • Human cases of highly pathogenic avian influenza a(h5n1) — California (CDC MMWR) 28:50
  • Influenza: Waste water scan for 11 pathogens (WastewaterSCan) 38:30
  • US respiratory virus activity (CDC Respiratory Illnesses) 38:30
  • Weekly surveillance report: cliff notes (CDC FluView) 38:30
  • RSV: Waste water scan for 11 pathogens (WastewaterSCan) 39:04
  • Estimated effectiveness of Nirsevimab against respiratory syncytial virus (JAMA Network) 39:16
  • Weekly US influenza surveillance report (CDC FluView)
  • US respiratory virus activity (CDC Respiratory Illnesses) 39:04
  • RSV-Network (CDC Respiratory Syncytial virus Infection) Waste water scan for 11 pathogens (WastewaterSCan) 39:04
  • COVID-19 deaths (CDC) 40:10
  • COVID-19 national and regional trends (CDC) 40:10
  • Wuhan market was epicenter of pandemic’s start (Nature) 41:10
  • COVID-origins study links raccoon dogs to Wuhan market (Nature) 41:10
  • What sparked the COVID pandemic? (Nature) 41:10
  • COVID-19 variant tracker (CDC) 43:03
  • SARS-CoV-2 genomes galore (Nextstrain)
  • Inhaled COVID vaccine (AeroVax) 44:35
  • Made-at-McMaster inhaled COVID-19 vaccine begins phase-2 human trial (McMaster University) 44:35
  • Where to get pemgarda (Pemgarda)
  • EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
  • Fusion center (Prime Fusions)
  • CDC Quarantine guidelines (CDC)
  • NIH COVID-19 treatment guidelines (NIH)
  • Risk of post-acute sequelae of COVID-19 and oral antivirals in adults aged over 60 years (International Journal of Infectious Diseases) 47:47
  • Letters read on TWiV 1200 50:18
  • Dr. Griffin’s COVID treatment summary (pdf)
  • Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

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