TWiV 821: Public clonotype #1
- October 24, 2021
- Tagged as: antibody, B cell, bat, coronavirus, COVID-19, germline antibody, Hendra virus, IgD, Nipah virus, paramyxovirus, rodent, SARS-CoV-2, somatic hypermutation, viral, virology, virus, viruses
A TWiV trio reveal the isolation of novel paramyxoviruses from rodents and bats in Arizona, and isolation of naive B cells from seronegative donors that produce germline encoded antibodies which engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses from bats.