Vincent and Amy explain how asthmatic bronchial smooth muscle increases rhinovirus replication in the bronchial epithelium, and mimicry of IL-17 by the ORF8 protein of SARS-CoV-2.
At the University of Wisconsin-Madison, Vincent meets up with one of his virology heroes, Roland R. Rueckert, to talk about his research and his second career as a forest manager.
At Europic 2018, a meeting on picornaviruses in the Netherlands, Vincent speaks with Sasha Gorbalenya, Jim Hogle, Ann Palmenberg and Frank van Kuppeveld about their careers and their research.
TWiV 455: Pork and genes
- August 20, 2017
- Tagged as: computer security, CRISPR/Cas9, DNA based exploit, IFIH1, loss of function, Mda5, organ transplant, PERV, PERV free pig, porcine endogenous retrovirus, remote code execution, respiratory syncytial virus, rhinovirus, severe viral respiratory infection, viral, virology, virus
Erin joins the TWiVirions to discuss a computer exploit encoded in DNA, creation of pigs free of endogenous retroviruses, and mutations in the gene encoding an innate sensor of RNA in children with severe viral respiratory disease.
TWiV 374: Discordance in B
- January 31, 2016
- Tagged as: 5'-tyrosyl DNA phosphodiesterase, activation-induced cytidine deaminase, AID, Burkitt, Burkitt's lymphoma, c-myc, cancer, coxsackievirus, Epstein-Barr virus, hypermutation, malaria, oncogene, picornavirus, Plasmodium falciparum, poliovirus, replication, rhinovirus, TDP2, translation, translocation, unlinkase, viral, virology, virus, viruses, VPg
The TWiVniks consider the role of a cell enzyme in removing a protein linked to the 5′-end of the picornavirus genome, and the connection between malaria, Epstein-Barr virus, and endemic Burkitt’s lymphoma.
The TWiVocateurs discuss how the RNA polymerase of enteroviruses binds a component of the splicing machinery and inhibits mRNA processing.
The TWiV gang reviews ten fascinating, compelling, and riveting virology stories from 2014.
Vincent, Alan, Rich and Kathy review a protease essential for influenza pathogenesis in mice, and directionality of rhinovirus RNA exit from the capsid.
Vincent and Rich discuss recovery of a hepatitis B viral genome from a 16th century Korean mummy, and personal omics profiling of an individual over a 14 month period.
Vincent visited Scotch Plains – Fanwood High School and talked about viruses with high school biology students.