proteasome | This Week in Virology

TWiV 524: Slicing and dicing with Raul

December 12, 2018
Tagged as: argonaute, cricket, dicer, drosophila, insect, proteasome, RNA interference, RNAi, ubiquitin, viral, virology, virus, viruses

Raul Andino joins Vincent and Amy to talk about the finding that a cricket paralysis virus protein restricts RNA-based immunity in insects by regulating the activity and stability of the Argonaute protein.

Lonya and Jeremy take the TWiV team beTWIXt primate immunodeficiency virus proteins Vpx and Vpr and how they counteract transcriptional repression of proviruses by the HUSH complex.

The TWiVers discuss the declining readability of scientific texts, and review the use of self-inactivating rabies virus for tracing neural circuits.

Netcast

TWiV 269: Herpesvirus stops a nuclear attack

January 26, 2014
Tagged as: acetylation, degradation, DNA, IFI16, innate immunity, interferon, nuclear localization signal, nucleus, proteasome, sensor, ubiquitin, viral, virology, virus

The complete TWiV team reviews evidence for sensing of herpesviral DNA in the nucleus by the cell protein IFI16.

Tag: proteasome

TWiV 524: Slicing and dicing with Raul

TWiV 516: HUSH little virus, don’t you transcribe

TWiV 461: Gotta trace them all!

TWiV 269: Herpesvirus stops a nuclear attack

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