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Tag: PMCA

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TWiV 426: I’m Axl, and I’ll be your cervid today

  • January 29, 2017
  • Tagged as: AXL, cervid, chronic wasting disease, Gas6, innate immunity, interferon, PMCA, prion, protein misfolding, SOCS-1, viral, virology, virus, virus entry, virus receptor, viruses, Zika virus
TWiV

The sages of TWiV explain how chronic wasting disease of cervids could be caused by spontaneous misfolding of prion protein, and the role of the membrane protein Axl in Zika virus entry into cells.

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TWiV 424: FLERVergnügen

  • January 15, 2017
  • Tagged as: evolution, fish foamy virus like retrovirus, FLERV, foamy virus, mad cow disease, Paleozoic, PMCA, prion, retrovirus, sCJD, spongiform encephalopathies, vCJD, viral, virology, virus, viruses
TWiV

Trudy joins the the TWiVlords to discuss new tests for detecting prions in the blood, and evidence showing that foamy retroviruses originated in the seas with their jawed vertebrate hosts at least 450 million years ago.

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