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Tag: human immunodeficiency virus

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TWiV 516: HUSH little virus, don’t you transcribe

  • October 21, 2018
  • Tagged as: chromatin, hiv, human immunodeficiency virus, HUSH complex, LINE-1, promoter, proteasome, provirus, siv, transcriptional repression, viral, virology, virus, viruses, Vpr, Vpx

Lonya and Jeremy take the TWiV team beTWIXt primate immunodeficiency virus proteins Vpx and Vpr and how they counteract transcriptional repression of proviruses by the HUSH complex.

2 Replies
  • Episodes
  • Netcast

TWiV 511: Accessory found guilty in DC

  • September 16, 2018
  • Tagged as: AIDS, dendritic cell vaccine, dNTP, hiv-1, HIV-2, human immunodeficiency virus, latent reservoir, myeloid cell, Ned Landau, restriction factor, reverse transcription, SAMHD1, siv, viral, virology, virus, viruses, Vpx

Ned Landau joins the TWiV team to discuss restriction of HIV replication by SAMHD1, and a viral antagonist that can be used to produce a dendritic cell vaccine.

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  • Netcast

TWiV 327: Does a gorilla shift in the woods?

  • March 8, 2015
  • Tagged as: APOBEC3G, cross-species, deamination, epidemic, gorilla, group O, hiv-1, human immunodeficiency virus, SIV-1, spillover, vif, viral, virology, virus, zoonosis

The eTWiVicators review evidence that the HIV-1 group O epidemic began with a single cross-species transmission of virus from western lowland gorillas.

3 Replies
  • Netcast

TWiV 326: Giving HIV a flat tyr

  • March 1, 2015
  • Tagged as: aav, adeno-associated virus, CD4, eCD4-Ig, gene therapy, hiv, human immunodeficiency virus, immunoadhesin, immunoglobulin, sCD4-Ig, SHIV, simian immunodeficiency virus, siv, viral, virology, virus

The sternutating TWiVers discuss preventing infection of cells and animals by a soluble CD4-CCR5 molecule that binds to HIV-1 virus particles.

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  • Netcast

TWiV 244: Back in the CVVR

  • August 4, 2013
  • Tagged as: adenovirus, AIDS, hiv, human immunodeficiency virus, innate immunity, poxvirus, STEP trial, Thai trial, Vaccine, vector, viral, virology, virus

This episode of TWiV was recorded before an audience at the Beth Israel Deaconess Medical Center, where Vincent and Alan spoke with Dan and Jeff about AIDS vaccines.

1 Reply
  • Netcast

TWiV 240: Virology in Vermont

  • July 7, 2013
  • Tagged as: arenavirus, BSL-3, deer mouse, hantavirus, hiv, human immunodeficiency virus, influenza, lipid rafts, sin nombre, tetraspannin, viral, virology, virus

Vincent travels to the University of Vermont to talk with Markus and Jason about their work on HIV, influenza virus, arenaviruses and hantaviruses.

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  • Netcast

TWiV 232: Gophers go viral

  • May 12, 2013
  • Tagged as: antiviral therapy, APOBEC, deamination, error threshold, hiv-1, human immunodeficiency virus, Institute of molecular virology, measles virus receptor, mutation, nectin-4, teaching, University of Minnesota, viral, virology, virus

Vincent meets up with Roberto, Reuben, Lou, and Leslie at the University of Minnesota to talk about their work on HIV-1, APOBEC proteins, measles virus, and teaching virology to undergraduates.

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