TWiV reviews heterosexual transmission of clade I Mpox virus, continued circulation of oropouche virus in South America, herpesviruses in South American fur seals and sea lions, sex-specific differences in physiological responses to SARS-CoV-2 infection, underdetected dispersal and extensive local transmission drove the 2022 Mpox epidemic, and a humanized mouse model for adenovirus-associated virus gene therapy.
TWiV reveals plankton-infecting relatives of herpesviruses in the sunlit oceans, and a vaccine encoding non-spike T cell antigens that protects animals from severe SARS-CoV-2 infection.
Felicia joins TWiV to discuss her career and her research on human cytomegalovirus, which infects most of us for our entire lives yet mainly causes disease in the immunosuppressed.
From the European Society for Clinical Virology 2022 Conference in Manchester UK, Vincent speaks with Emma Thomson about the recent outbreak of pediatric hepatitis of unknown etiology and the finding that it is linked to infection by adenovirus-associated virus 2.
TWiV reviews Michael Worobey’s dissection of the early COVID-19 cases in Wuhan, and the discovery that herpesviruses assimilate cellular kinesin to produce motorized virus particles.
Vincent speaks with virologists at the University of Nevada at Reno about their careers and their work on herpesviruses, arboviruses, and the development of diagnostics for infectious diseases.
The TWiV team reveals the protein corona that surrounds virus particles and influences infectivity and amyloid aggregation, and a proofreading-impaired herpesvirus that produces quasispecies-like populations.
Vincent travels to Microbiotix, Inc, a biopharmaceutical company in Worcester, MA to speak with four members of the company about their discovery and development of small molecule drugs that target serious infectious diseases.
The TWiV crew reveal a unique portal on the calcivirus capsid formed upon receptor engagement, and the regulation of interferon responses in virus-infected cells by methylation of mRNA.
The TWiVosophers review the Chinese plasma virome revealed by non-invasive prenatal testing, and a new filovirus genome from bats in China.
The Hosts of TWiV
Vincent Racaniello, Ph.D.
Brianne Barker, Ph.D.
Rich Condit, Ph.D.
Dickson D.
Despommier, Ph.D.
Alan Dove, Ph.D.
Daniel Griffin, M.D.,
Ph.D., CTropMed CTH
Angela Mingarelli, DVM
Jolene Ramsey, Ph.D.
Kathy Spindler, Ph.D.