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Tag: filovirus

  • Episodes
  • Netcast

TWiV 743: Shape-shifting viruses

  • April 15, 2021
  • Tagged as: coronavirus, COVID-19, ebolavirus, filamentous virus, filovirus, influenza virus, pandemic, pleomorphic virus particle, SARS-CoV-2, Vaccine, viral, virology, virus, viruses

The TWiVsters explain how the shape of pleomorphic virus particles – spherical or filamentous – determines the probability of virus attachment and fusion, and resistance to selective pressure such as antibodies that block cell entry.

7 Replies
  • Episodes
  • Netcast

TWiV 533: Recurring threads

  • February 3, 2019
  • Tagged as: ebola virus, filovirus, hepatitis b virus, herpesvirus, Mengla virus, minigenome, non-invasive prenatal testing, NPC1, plasma virome, Rousettus bat, viral, virology, virus, viruses, zoonotic

The TWiVosophers review the Chinese plasma virome revealed by non-invasive prenatal testing, and a new filovirus genome from bats in China.

1 Reply
  • Netcast

TWiV 415: Ebola pipettors and the philosopher’s clone

  • November 13, 2016
  • Tagged as: adaptation, amino acid, ebola virus, filovirus, glycoprotein, mutation, NPC1, spillover, viral, virology, virus, viruses, zoonosis
TWiV

Jeremy, Aaron, and Ted join the TWiV team to discuss their work on identifying a single amino acid change in the Ebola virus glycoprotein from the West African outbreak that increases infectivity in human cells.

1 Reply
  • Netcast

TWiV 394: Cards in a hand

  • June 18, 2016
  • Tagged as: cryoEM, ebolavirus, filovirus, Marburg virus, protein, protein structure, structural biology, viral, virology, virus, viruses, X-ray structure
TWiV

Vincent and Alan speak with Erica about her career and her work on understanding the functions of proteins of Ebolaviruses, Marburg virus, and other hemorrhagic fever viruses, at ASM Microbe 2016 in Boston, MA.

2 Replies
  • Netcast

TWiV 309: Ebola email

  • November 2, 2014
  • Tagged as: aerosol, asymptomatic, body fluids, contact, ebola virus, ebolavirus, filovirus, hemorrhagic fever, incubation period, PCR, quarantine, semen, sexual transmission, transmission, viral, virology, virus

The TWiVocytes answer questions about Ebola virus, including mode of transmission, quarantine, incubation period, immunity, and much more.

6 Replies
  • Netcast

TWiV 297: Ebola! Don’t panic

  • August 10, 2014
  • Tagged as: antiviral, Ebola, ebolavirus, filovirus, Guinea, hemorrhagic fever, Liberia, Reston, Sierra Leone, Vaccine, viral, virology, virus, Zaire

The TWiVites present an all-ebolavirus episode, tackling virology, epidemiology, and approaches to prevention and cure that are in the pipeline.

11 Replies
  • Netcast

TWiV 283: No Reston for the weary

  • May 4, 2014
  • Tagged as: BSL-4, ebola virus, ebolavirus, emerging infection, filovirus, Guinea, Marburg virus, NEIDL, outbreak, Reston virus, viral, virology, virus, Zaire virus

Jens speaks with the TWiV team about filoviruses, including the recent Ebola virus outbreak in Guinea.

6 Replies
  • Netcast

TWiV 200: Threading the NEIDL

  • September 23, 2012
  • Tagged as: arenavirus, biocontainment, biodefense, bioterrorism, bsl2, bsl3, bsl4, containment facility, filovirus, NEIDL, niaid, select agent, viral, virology, virus

Vincent, Alan, and Rich celebrate the 200th episode of TWiV by visiting the National Emerging Infectious Diseases Laboratories at Boston University Medical Center, where they meet with Elke, Paul, and Ron to talk about building and working in a BSL4 facility.

12 Replies
  • Netcast

TWiV 196: An arena for snakes

  • August 19, 2012
  • Tagged as: annulated tree boa, arenavirus, boa constrictor, derisi laboratory, filovirus, inclusion body disease, python, reptile, snake, viral, virology, virus

The TWiVites meet with Mark Stenglein and Joseph DeRisi to discuss their discovery of a novel arenavirus in snakes with inclusion body disease.

4 Replies
  • Netcast

TWiV 91: You’re an ERVous wreck

  • July 18, 2010
  • Tagged as: endogenous retrovirus, erv, filovirus, herv, integration, nirv, retrovirus, venter, viral, virology, virus

Vincent, Dickson, Alan, Rich and Welkin discuss the nature, origin, and evolution of endogenous retroviruses (ERVs), and the recent finding of endogenous filovirus genomes in mammals.

5 Replies

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