TWiV revisits chronic wasting disease of cervids and the ability of the prions to infect meadow voles and raccoons, and the suggestion that stochastic assembly of influenza virus particles may play a role in phenotypic diversity.
TWiV 426: I’m Axl, and I’ll be your cervid today
- January 29, 2017
- Tagged as: AXL, cervid, chronic wasting disease, Gas6, innate immunity, interferon, PMCA, prion, protein misfolding, SOCS-1, viral, virology, virus, virus entry, virus receptor, viruses, Zika virus
The sages of TWiV explain how chronic wasting disease of cervids could be caused by spontaneous misfolding of prion protein, and the role of the membrane protein Axl in Zika virus entry into cells.
The TWiVerinoes discuss the potential for prion spread by plants, global circulation patterns of influenza virus, and the roles of Argonautes and a viral protein in RNA silencing in plants.
Vincent, Alan, and Marc talk about chronic wasting disease of deer caused by prions, blocking the semen-derived enhancer of HIV infection with surfen, and making green transgenic rabbits using a lentiviral vector.