TWiV 40: Tamiflu in the water

CV6_outside1_immatureHosts: Vincent Racaniello, Dick Despommier, and Alan Dove

Vincent, Dick, and Alan consider Reston ebolavirus in swine, historical perspective of H1N1 influenza virus emergence and circulation, Tamiflu-resistant H1N1, Tamiflu in Japanese river waters, transmission of H1N1 virus in ferrets, and pneumonia and respiratory failure from H1N1 in Mexico.

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Alan Coming to Life by Christiane Nusslein-Volhard
Dick Monsters Inside Me from Discovery Channel
Vincent Microbeworld

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TWiV 39: Virus structure

Hosts:Vincent Racaniello and Dick Despommier

Vincent and Dick discuss virus structure and answer listener questions.

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Dick Visual Explanations by Edward R. Tufte
Vincent The Youngest Science by Lewis Thomas

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TWiV 38: Measles

child-with-measlesHosts: Vincent Racaniello and Glenn Rall

Vincent and Glenn Rall chat about koi herpesvirus, H1N1 influenza vaccine produced in insect cells, attack by a rabid raccoon, and measles.

Click the arrow above to play, or right-click to download TWiV #38 (63 MB .mp3, 91 minutes)

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Glenn Riddled with Life by Marlene Zuk
Vincent All the Virology on the WWW

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TWiV 37: Open access

Hosts: Vincent Racaniello, Alan Dove, and Eric O. Freed

Vincent, Alan, and Eric Freed talk about vesivirus contamination of bioreactors, pandemic influenza, maximizing the effect of vaccination by targeting children, chikungunya virus, and open access scientific journals.

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Alan Forrest Mims (website)
Vincent The Machinery of Life by David S. Goodsell

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TWiV 36: Pandemic

Hosts: Vincent Racaniello, Alan Dove, Dick Despommier, and Hamish Young

Vincent, Alan, Dick, and Hamish Young discuss the 2009 influenza pandemic, first 2009 H1N1 vaccine, hunting mosquitoes with midges, vaccine-associated polio in India, and adenoviruses.

Click the arrow above to play, or right-click to download TWiV #36 (64 MB .mp3, 93 minutes)

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Dick The World’s Water by Peter H. Gleick
Hamish Guns, Germs, and Steel by Jared Diamond; Complications by Atul Gawande
Alan Eurekalert
Vincent Respectful Insolence

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TWiV 35: Much achoo about nothing

Hosts: Vincent Racaniello, Alan Dove, Dick Despommier, and Richard Kessin

Vincent, Alan, Dick, and Richard Kessin talk about Lujo virus, a new arenavirus, influenza, WHO rewriting pandemic rules, adjuvants, and a brief history of microbiology.

Click the arrow above to play, or right-click to download TWiV #35 (57 MB .mp3, 82 minutes)

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Links for this episode:

  • Lujo virus, a new arenavirus
  • Is CDC too optimistic about influenza?
  • WHO to rewrite pandemic rules
  • Adjuvant at wikipedia
  • Avery, MacLeod, McCarty 50th anniversary (pdf)
  • Pasteur’s swan-neck flask

 

pasteur-swan-neck-flask

Broth was placed in a flask, boiled, and the neck was heated and drawn out. The broth was open to the air, but remained sterile as long as microbe-containing dust collected in the neck and did not reach the liquid.

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Dick Three papers on origins of infectious diseases (one, two, three)
Rich An Imperfect Lens by Anne Roiphe
Alan Zotero, a FireFox plugin
Vincent e! Science News

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TWiV 34: Arsenic and facemasks

Hosts: Vincent Racaniello, Alan Dove, and Stephen Morse

Vincent, Alan, and Stephen Morse discuss progressive vaccinia in a smallpox vaccinee, arsenic and influenza in mice, facemasks and flu transmission, and antigenic and genetic analyses of the new H1N1 influenza virus.

Click the arrow above to play, or right-click to download TWiV #34 (54 MB .mp3, 78 minutes)

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Alan Org-Mode
Vincent Human/Swine A/H1N1 Influenza Origins and Evolution
Stephen The Origin of Species by Charles Darwin

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TWiV 33: Live in Philly

Hosts: Vincent Racaniello, Alan Dove, Dick Despommier, and Raul Andino

Vincent, Alan, Dick, and Raul Andino recorded TWiV live at the ASM General Meeting in Philadelphia, where they discussed increased arterial blood pressure caused by cytomegalovirus infection, restriction of influenza replication at low temperature by the avian viral glycoproteins, first isolation of West Nile virus in Pennsylvania, and current status of influenza.



Click the arrow above to play, or right-click to download TWiV #33 (51 MB .mp3, 74 minutes)

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Dick – National Museum of the History of Science and Medicine, Leiden
Alan – Beginning Mac OS X Programming
Vincent – Vaccinated by Paul Offit
Raul – HubbleSite

Thanks to Chris Condayan and ASM for making TWiV live possible. Recorded and edited by Chris Condayan and Ray Ortega.

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TWiV 32: Influenza in silico

Hosts: Vincent Racaniello, Alan Dove, and Raul Rabadan

Vincent, Alan, and Raul Rabadan converse about polio survivors in iron lungs, bocavirus, structure of mimivirus, and genome sequence analysis of influenza H1N1 viruses.

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Alan The Franklin Institute Science Museum in Philadelphia
Vincent Pi Cubed for iPhone/iPod Touch (Sunset Lake Software, $9.99)
Raul Science and New England Journal articles on H1N1 influenza

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TWiV 31: Fever plus cough or sore throat

Hosts: Vincent Racaniello, Dick Despommier, Alan Dove, and Marc Pelletier

Vincent, Dick, Alan, and Marc Pelletier summarize the past week’s influenza H1N1 activity, and discuss parvovirus infection of dogs and humans.

Click the arrow above to play, or right-click to download TWiV #31 (51 MB .mp3,  73 minutes)

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Links for this episode:

  • CDC and WHO web pages on the new influenza strain
  • MMWR update on influenza
  • Excellent influenza vaccine timeline at USA Today
  • Sequences of influenza isolates are at NCBI and GISAID (registration required)
  • Euthanizing dogs due to canine parvovirus
  • Novel bocavirus associated with acute gastroenteritis in Australian children
  • Viral genes that confer transmission of avian influenza virus through the air – PNAS
  • Influenza in feral pigs (J Wildlife Dis)

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Marc Celestia, an application
Dick US Geological Survey website
Alan Society for Amateur Scientists website
Vincent Sneeze, an online game

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Inside a BSL-4 laboratory

TWiV visits the NEIDL