TWiP 13: Toxoplasmosis

toxo_invasionHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson continue their discussion of the obligate intracellular protozoan Toxoplasma gondii with a consideration of the clinical consequences of infection and pathogenesis.

Download TWiP #13 (61 MB .mp3, 84 minutes)

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TWiP 12: Toxoplasma gondii

t_gondii_tachyzoiteHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson introduce the obligate intracellular protozoan Toxoplasma gondii, one of the most successful parasites on earth.

Download TWiP #12 (70 MB .mp3, 98 minutes)

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TWiP 11: One times three million

malaria_pathogenesisHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson continue their discussion of malaria, with emphasis on clinical aspects of the disease.

Download TWiP #11 (63 MB .mp3, 87 minutes)

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TWiP 10: Plasmodium life cycle

plasmodium_bloodHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson trace the life cycle of Plasmodium in a mosquito and in a human host.

Download TWiP #10 (62 MB .mp3, 86 minutes)

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  • Mosquito cycle – sporogany (jpg)
  • Plasmodium falciparum cycle (jpg)
  • Plasmodium vivax cycle (jpg)
  • Plasmodium falciparum ring forms and gametocytes in blood (jpg)
  • Plasmodium stages (jpg)
  • Letters read on TWiP 10

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TWiP 9: Mala aria

anopheles_gambiaeHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson move on to protozoan parasites with a discussion of the early history of malaria.

Download TWiP #9 (59 MB .mp3, 82 minutes)

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TWiP 8: Frog legs and parasite tales

spirometra_mansonoidesHosts: Vincent Racaniello and Dickson Despommier

Dickson reads his story about sparganosis caused by the diphyllobothroid tapeworm Spirometra mansonoides.

Download TWiP #8 (60 MB .mp3, 83 minutes)

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TWiP 7: Tapeworms are fantastic!

tapewormsHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson continue their discourse on tapeworms, covering the fish and dog varieties.

Download TWiP #7 (70 MB .mp3, 97 minutes)

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  • FAT the enemy that is shortening your life is BANISHED. How? With sanitized tapeworms. Easy to swallow! (jpg).
  • D. latum life cycle (jpg)
  • D. latum adult (jpg)
  • Diphyllobothrim proglottid (jpg)
  • Diphyllobothrim bothria (jpg)
  • Coracidium hatching from egg (jpg)
  • Dog tapeworm life cycle (jpg)
  • The Alien lifecycle (jpg)

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TWiP 6: Tapeworms, the long and short of it

taenia_saginata_adultHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dick talk about the anatomy and life cycle of beef and pork tapeworms, and why House was wrong about neurocysticercosis.

Download TWiP #6 (73 MB .mp3, 101 minutes)

Links for this episode:

  • Taenia saginata life cycle (jpg)
  • Taenia saginata adult (jpg)
  • Taenia saginata scolex (jpg)
  • Taenia saginata gravid proglottid (jpg)
  • Taenia solium life cycle (jpg)
  • Taenia solium adult (jpg)
  • Taenia solium scolex (jpg)
  • Facial cancer in Tasmanian devils (thanks PhogDog!)

Science Picks

Dickson Peace through vaccine diplomacy by Peter Hotez
Vincent Parasite Rex by Carl Zimmer

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TWiP 5 – The nurse cell

ncparacomp1Hosts: Vincent Racaniello and Dickson Despommier

Vincent and Dick discuss the nurse cell, a unique structure formed in the host muscle by Trichinella species.

Download TWiP #5 (57 MB .mp3, 79 minutes)

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Weekly Science Picks

Dickson Every Living Thing by Rob Dunn

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TWiP 4: Trichinella life cycle

lifecycleHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson trace the life cycle of Trichinella spiralis in an infected host.

Download TWiP #4 (59 MB .mp3, 82 minutes)
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Links for this episode:

  • Trichinella life cycle (jpg)
  • Newborn larva entering muscle cell (jpg)
  • Adult T. spiralis in columnar epithelial cell (jpg)
  • Adult female T. spiralis (jpg)
  • Infective first stage T. spiralis larva in Nurse cell in muscle tissue (jpg)
  • Adult female T. spiralis with fully formed larvae in uterus (jpg)
  • Adult male T. spiralis with claspers on tail (jpg)
  • Clinical correlations in trichinosis (jpg)
  • Letters read on TWiP #4

Weekly Science Picks

Dickson David Scharf’s pictures of microbial life
Vincent The Nobel Laureate Meetings at Lindau

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Music by Ronald Jenkees

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