TWiN describes experiments demonstrating that gut injection of alpha-synuclein fibrils in mice converts endogenous alpha-synuclein to a pathologic form that spreads to the brain and leads to features of Parkinson’s disease.
Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison
Click arrow to play
Download TWiN 030 (44 MB .mp3, 74 min)
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Links for this episode
- Gut-brain alpha-synuclein transport in PD (Neuron) 4:23, 36:25
- Gut has a mind of its own (Colbert Report) 1:04:10
- Timestamps by Jolene. Thanks!
Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv