TWiN 30: Gut to brain spread of alpha-synuclein in Parkinson’s disease

May 24, 2022

TWiN describes experiments demonstrating that gut injection of alpha-synuclein fibrils in mice converts endogenous alpha-synuclein to a pathologic form that spreads to the brain and leads to features of Parkinson’s disease.

Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

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Download TWiN 030 (44 MB .mp3, 74 min)
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Music is by Ronald Jenkees

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