The TWiM team reveals the genetic mysteries of the Dead Sea Scrolls from sequencing of DNA, and 100 million year old living bacteria recovered from marine sediments.
Harris joins Vincent, Elio, and Michael to describe multiplex automated genome engineering, a method for targeting many modifications in a population of bacterial cells.
Vincent meets up with Rob Knight to talk about the technology that has fueled his drive to sequence the Earth and its inhabitants.
Vincent, Elio, and Michele review how horizontal gene transfer from bacteria to an insect genome enables a tripartite nested mealybug symbiosis, and how probiotic bacteria work by competing for iron in the intestine.
Vincent, Michael, and Ivo review the requirement for segmented, filamentous bacteria for the induction of a specific type of helper T cell in the gut.
On episode #19 of the podcast This Week in Microbiology, Vincent, Michael, Elio, and Jo discuss the genome sequence of Y. pestis from victims of the Black Death, and the effect of diet on gut microbial enterotypes.
On episode #12 of the podcast This Week in Microbiology, Vincent, Margaret, Michael and Elio review the use of photothermal nanoblades to dissect the Burkholderia intracellular life cycle, and manipulation of chromosomes in vivo for genome-wide codon replacement in E. coli.
On episode #5 of the podcast This Week in Microbiology, Vincent, Cliff, Michael and Ron discuss the genome sequence of a mercury-methylating bacterium and the antimicrobial effects of nanoparticles.
On episode #3 of the podcast This Week in Microbiology, Vincent, Jo, Cliff, and Ron explore the genome analysis done in support of the Amerithrax investigation, and an insecticidal enterotoxin-deficient mutant of Bacillus thurigiensis.
About the Hosts of TWiM
Vincent Racaniello, Ph.D. (@profvrr) is Higgins Professor of Microbiology & Immunology at Columbia University Medical Center. He has been studying viruses for over 40 years. He teaches virology to undergraduate and graduate students, as well as medical, dental, and nursing students. His lectures are available online at iTunes University, YouTube, and Coursera.
Michael Schmidt, Ph.D. (TWiM) is the Professor and Vice Chairman of Microbiology and Immunology and Director of the Office of Special Programs at the Medical College of South Carolina. Dr. Schmidt is leading a team of infectious disease specialists from three health sciences centers and engineers from industry.