The TWiM team reviews the movie Jezebel, played against the background of the yellow fever epidemic of 1853 in New Orleans, and prokaryotic viperins, ancestors of the eukaryotic enzymes that synthesize antiviral molecules.

TWiM explores the use of a bacterial protein to make highly conductive microbial nanowires, and how modulin proteins seed the formation of amyloid, a key component of S. aureus biofilms.

Sam Sternberg discusses his work on exploring and exploiting CRISPR-Cas immune systems, beginning as a graduate student with Jennifer Doudna, at a biotech start-up, and in his laboratory at Columbia University.