TWiM 72: The benefits of virulence

Mammalian Drosophila intestineHosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt and Michele Swanson

Vincent, Elio, Michael, and Michele review how microbial virulence can be increased as a consequence of community surveillance and adaptation to macrophages.

Right click to download TWiM#72 (53 MB .mp3, 74 minutes).

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TWiM 71: Colon cancer’s little shop of horrors

Butyric acidHosts: Vincent Racaniello, Michael Schmidt and Michele Swanson

Vincent, Michael, and Michele explain how the gut microbiome modulates colon tumorigenesis, and regulation of intestinal macrophage function by the microbial metabolite butyrate.

Right click to download TWiM#71 (57 MB .mp3, 78 minutes).

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TWiM 70: A paroxysmal cough

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt and Michele Swanson

Vincent, Elio, Michael, and Michele discuss evidence that the acellular pertussis vaccine fails to prevent infection and transmission in nonhuman primates, and the use of bacterial cytological Pertussis world map by-wiki-Lokal Profilprofiling to identify pathways targeted by antibiotics.

Right click to download TWiM#70 (53 MB .mp3, 73 minutes).

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TWiM 69: Bacterial DNA in the human genome

acinetobacterHosts: Vincent Racaniello, Elio Schaechter, Jo Handelsman and Michele Swanson

Vincent, Elio, Jo, and Michele review evidence for bacterial DNA integrated into the human genome, and control of the symbiont population in an insect midgut.

Right click to download TWiM #69 (51 MB .mp3, 71 minutes).

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TWiM 68: The fungus among us

tested surfacesHosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt and Michele Swanson.

Vincent, Elio, Michael, and Michele discuss the amazingly high level of intergenera gene exchange among haloarchaea in an Antarctic lake, and the diversity of fungi on residential surfaces and the human forehead.

Right click to download TWiM #68 (51 MB .mp3, 71 minutes).

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TWiM 67: Black mushrooms and RNA thermosensors

auricularia auricula-judaeHosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

Vincent, Elio, and Michael discuss how temperature triggers Neisseria menigitidis immune evasion, and protection of mice from ionizing radiation by feeding them black mushrooms.

Right click to download TWiM #67 (55 MB .mp3, 75.5 minutes).

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TWiM 66: The shape of a container

outer membrane vesiclesHosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt and Michele Swanson

Vincent, Elio, Michael, and Michele discuss the curious outer membrane vesicles of Neisseria meningitidis, and sources of Clostridium difficile infection revealed by genome sequencing.

Right click to download TWiM #66 (50 MB .mp3, 68 minutes).

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TWiM 65: Leanness is transmissible

two mice

Hosts: Vincent Racaniello and Michele Swanson.

Vincent and Michelle reveal how the human gut microbiota can modulate obesity in mice.

Right click to download TWiM #65 (35 MB .mp3, 51 minutes).

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TWiM 64: URI and UTI at ICAAC in Denver

Hosts: Vincent Racaniello, Michael Schmidt, James Gern, and James R. Johnson.

Vincent and Michael recorded this episode at the 53rd ICAAC in Denver, where they spoke with James Gern and James Johnson about rhinoviruses and extra-intestinal pathogenic E. coli.



Right click to download TWiM #64 (56 MB .mp3, 77 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

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TWiM 63: Superantigens, S. aureus, and the armpit microbiome

grapes

Hosts: Vincent Racaniello, Michael Schmidt and Michele Swanson

Vincent, Michael, and Michelle discuss how a Staphylococcus aureus superantigen is critical for pathogenesis in a rabbit model, and the relationship of body odor to the axilla microbiome.

Right click to download TWiM #63 (59 MB .mp3, 85 minutes).

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode:

Send your microbiology questions and comments to [email protected]

The Hosts of TWiM

Petra Levin, Ph.D.


Michele Swanson, Ph.D.


Michael G. Schmidt, Ph.D.


Vincent Racaniello, Ph.D.


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Please note that content in MicrobeTV podcasts should not be construed as medical advice.