TWiM 125: A minimal cell operating system

Syn1.0Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

A deep sequencing study of commercially available probiotics, and design and synthesis of a minimal bacterial genome are the topics tackled by Vincent, Michael, and Michele on this episode of TWiM.

Right click to download TWiM#125 (42 MB .mp3, 58 minutes)

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to [email protected].

TWiM 124: Fungal pirates

Blastomyces dermatitidisHosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Vincent, Michael, and Michele reveal how a fungal protease blunts the innate immune response and promotes pathogenicity.

Right click to download TWiM#124 (44 MB .mp3, 63 minutes)

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to [email protected].

TWiM 123: A microbial MAGE

Microbial tradingHosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

Guest: Harris Wang

Harris joins Vincent, Elio, and Michael to describe multiplex automated genome engineering, a method for targeting many modifications in a population of bacterial cells.

Right click to download TWiM#123 (52 MB .mp3, 76 minutes)

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by Microbe Magazine Podcast and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to [email protected].

TWiM 122: Mayonii, microRNAs, and the microbiome

Borrelia burgdorferiHosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome.

Right click to download TWiM#122 (46 MB .mp3, 64 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by Microbe Magazine Podcast and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to [email protected].

TWiM 121: A plague of pathogens

Host: Vincent Racaniello

Guests: Rebekah Kading and Wyndham Lathem

From the ASM Biodefense and Emerging Diseases Research meeting, Vincent speaks with Rebekah and Wyndham about their work on Rift Valley Fever virus and other vector-borne pathogens, and the evolution and pathogenesis of Yersinia pestis, the agent of plague.

Right click to download TWiM#121 (42 MB .mp3, 58 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Grant Writing Webinar and 32nd Clinical Virology Symposium

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to [email protected].

TWiM 120: Snakes in trouble

snake fungal diseaseHosts: Vincent Racaniello and Elio Schaechter

Vincent and Elio marvel in the finding that a phage tail-like structure from a marine bacterium stimulates tubeworm metamorphosis, and reveal Ophidiomyces as a cause of snake fungal disease.

Right click to download TWiM#120 (35 MB .mp3, 49 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Grant Writing Webinar and 32nd Clinical Virology Symposium

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to [email protected].

TWiM 119: Power of one

TWiM 119Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter

The microbophiles investigate the ratio of bacterial to human cells in our bodies, and how placing solar panels on a bacterium enables it to carry out photosynthesis.

Right click to download TWiM#119 (46 MB .mp3, 73 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Grant Writing Webinar and 32nd Clinical Virology Symposium

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to [email protected].

TWiM 118: Spore-drops keep fallin’ on my head

Spore catapultHosts: Vincent Racaniello, Elio Schaechter and Michele Swanson

On the last episode for 2015, Vincent, Elio, and Michele discuss how soil amoeba hunt nematodes in packs, and the role of mushrooms as rainmakers.

Right click to download TWiM#118 (47 MB .mp3, 66 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Microbe 2016 and ASM Biodefense

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to [email protected].

TWiM 117: Finding the comammox

Nitrogen CycleHosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Michele Swanson.

The TWiM team marvels over the finding of a completely nitrifying Nitrospira, and horizontal gene transfer from Wolbachia into an animal genome.

Right click to download TWiM#117 (51 MB .mp3, 71 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Microbe 2016 and ASM Biodefense

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to [email protected].

TWiM 116: Chewates and coconuts

coconut oilHosts: Vincent Racaniello, Elio Schaechter and Michele Swanson

The TWiMeriti reveal a Brazilian social bee that must cultivate a fungus to survive, and diet-mediated reduction in gut colonization by Candida albicans.

Right click to download TWiM#116 (41 MB .mp3, 61 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Biodefense and the 32nd Clinical Virology Symposium.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to [email protected]

The Hosts of TWiM

Petra Levin, Ph.D.


Michele Swanson, Ph.D.


Michael G. Schmidt, Ph.D.


Vincent Racaniello, Ph.D.


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